Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
FlixBus San Francisco San Diego recent customer reviews
There was a strong smell coming from the toilet. No electric power supply, no WiFi. And very rude driver (only the first)
2 out of 5 stars
Enrico C.
Los asientos son muy incómodos, casi no se reclinan. Decía que el viaje era directo e hizo muchas paradas y en cada vez prendían las luces lo que hacía imposible poder descansar (elegimos viajar de noche porque era el único que iba directo). No fue una buena experiencia.
2 out of 5 stars
Maria Nazaret C.
Worse service I ever seen. I spend five and an half hours in Los Angeles. No one wants to help me even after I called the customer service. She said her supervisor will contact me and send me my ticket. Nothing happened and no one contacted me. I will never take Greyhound buses again.😠😠
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
FlixBus San Francisco San Diego recent customer reviews
There was a strong smell coming from the toilet. No electric power supply, no WiFi. And very rude driver (only the first)
2 out of 5 stars
Enrico C.
Los asientos son muy incómodos, casi no se reclinan. Decía que el viaje era directo e hizo muchas paradas y en cada vez prendían las luces lo que hacía imposible poder descansar (elegimos viajar de noche porque era el único que iba directo). No fue una buena experiencia.
2 out of 5 stars
Maria Nazaret C.
Worse service I ever seen. I spend five and an half hours in Los Angeles. No one wants to help me even after I called the customer service. She said her supervisor will contact me and send me my ticket. Nothing happened and no one contacted me. I will never take Greyhound buses again.😠😠
Based on 5421 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $69
FlixBus San Francisco San Diego recent customer reviews
There was a strong smell coming from the toilet. No electric power supply, no WiFi. And very rude driver (only the first)
2 out of 5 stars
Enrico C.
Los asientos son muy incómodos, casi no se reclinan. Decía que el viaje era directo e hizo muchas paradas y en cada vez prendían las luces lo que hacía imposible poder descansar (elegimos viajar de noche porque era el único que iba directo). No fue una buena experiencia.
2 out of 5 stars
Maria Nazaret C.
Worse service I ever seen. I spend five and an half hours in Los Angeles. No one wants to help me even after I called the customer service. She said her supervisor will contact me and send me my ticket. Nothing happened and no one contacted me. I will never take Greyhound buses again.😠😠
Busbud helps you find a bus from San Francisco to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from San Francisco to San Diego from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from San Francisco to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in San Francisco and San Diego?
Frequently asked questions for your trip San Francisco, US - San Diego, CA, US
How far is San Francisco from San Diego?
The distance separating San Francisco and San Diego is 458 miles (739 km).
What are the departure and arrival stations when taking the bus from San Francisco to San Diego?
Most of the buses traveling from San Francisco to San Diego leave from Hyde/Beach (Fisherman's Wharf) and arrive at Mission Valley Sheraton. These are the most popular departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in San Diego?
Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are Botanical Building and Lily Pond, Coronado, SeaWorld San Diego, San Diego Zoo and La Jolla Cove.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/23
$65
08/24
$65
Today
$65
08/26
$62
08/27
$59
08/28
$65
08/29
$65
08/30
$62
The cheapest trip from San Francisco, US to San Diego, CA, US was searched and found on Aug 27, 2025 with a price of $59
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to San Diego, CA, US, as early as possible.
You can expect to pay from $59 to $181 for a bus ticket from San Francisco, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $59 which is on 2025-08-27.
Usually Amtrak, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Francisco and San Diego!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Francisco to San Diego, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Francisco to San Diego that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from San Francisco to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Will you be returning to San Francisco, US by bus?
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.