What is the travel distance from Louisville to Chicago?

About 268 miles (432 km) separate Louisville and Chicago.

What are the departure and arrival stations when taking the bus from Louisville to Chicago?

The majority of buses traveling from Louisville to Chicago start their journey at Louisville Greyhound Bus Station and wind up at Downtown Greyhound Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in Chicago?

Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Cloud Gate, Lincoln Park Conservatory, Museum of Contemporary Art, Shedd Aquarium and Museum of Science and Industry.

Bus Louisville to Chicago from $36 | Refundable Tickets

ThuSep 4

FriSep 5

from $51

SatSep 6

SunSep 7

MonSep 8

TueSep 9

WedSep 10

ThuSep 11

Cheap buses leaving Friday

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: September 5 at 8:00am
Departure city: Louisville
Departure location: Louisville, KY
Arrival time: September 5 at 2:00pm
Destination city: Chicago
Destination location: Chicago 95Th & Dan Ryan
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 7h
This trip is recommended because it is: Fastest
Departure time: September 5 at 7:30pm
Departure city: Louisville
Departure location: Louisville, KY
Arrival time: September 5 at 11:50pm
Destination city: Chicago
Destination location: Chicago 95Th & Dan Ryan
Operated by: FlixBus
Vehicle: BusDuration: 5h 20m
Departure time: September 5 at 2:55am
Departure city: Louisville
Departure location: Louisville, KY
Arrival time: September 5 at 7:55am
Destination city: Chicago
Destination location: Chicago (Union Station), IL
Operated by: Amtrak
Vehicle: BusDuration: 6h
Departure time: September 5 at 2:55am
Departure city: Louisville
Departure location: Louisville, KY
Arrival time: September 5 at 8:15am
Destination city: Chicago
Destination location: Downtown Greyhound Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 6h 20m
Departure time: September 5 at 4:50am
Departure city: Louisville
Departure location: Louisville, KY
Arrival time: September 5 at 11:30am
Destination city: Chicago
Destination location: Downtown Greyhound Station
Operated by: FlixBus
Vehicle: BusDuration: 7h 40m

Accepted payments

Bus Louisville to Chicago: Trip Overview

Average ticket price$58

Average bus trip duration6h 55m

Number of daily buses17

Earliest bus departure2:50am

Distance259 miles (417 km)

Latest bus departure7:30pm

Compare bus companies

Greyhound

3.5/587,229 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound Louisville Chicago recent customer reviews

The bus was 30 minutes late, there were too many people on board, leaving a couple to stand. Then the driver had to slam on his brakes and I don’t know how the standing people didn’t get thrown up front. At one point the driver was getting on the interstate going the wrong way, until people started yelling at him. Absolutely not the best ride.

Reese W.

October 25, 2023

Mobile chargers and WiFi was not working at all despite the fact that same were informed to be working conditions

Muhammad Amir B.

February 6, 2020

I had a stop over at Indianapolis, IN.of supposedly for 30min.on my way to Chgo.but somehow the mgr said the bus to Chgo.was delayed for 1hr coming from Cincinnati then later on the driver of my bus said that it's not delayed and it's leaving! I almost miss my bus! So much confusion! Why can't they get their schedule right! Also the toilet on the bus has no more toilet paper plus it's too dark in there. I will never take this bus again! This was my first experience (in a very long time )and my last! Pls get your schedules right!

Phoebe T.

November 3, 2019

FlixBus

3.5/510,364 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound Louisville Chicago recent customer reviews

The bus was 30 minutes late, there were too many people on board, leaving a couple to stand. Then the driver had to slam on his brakes and I don’t know how the standing people didn’t get thrown up front. At one point the driver was getting on the interstate going the wrong way, until people started yelling at him. Absolutely not the best ride.

Reese W.

October 25, 2023

Mobile chargers and WiFi was not working at all despite the fact that same were informed to be working conditions

Muhammad Amir B.

February 6, 2020

I had a stop over at Indianapolis, IN.of supposedly for 30min.on my way to Chgo.but somehow the mgr said the bus to Chgo.was delayed for 1hr coming from Cincinnati then later on the driver of my bus said that it's not delayed and it's leaving! I almost miss my bus! So much confusion! Why can't they get their schedule right! Also the toilet on the bus has no more toilet paper plus it's too dark in there. I will never take this bus again! This was my first experience (in a very long time )and my last! Pls get your schedules right!

Phoebe T.

November 3, 2019

Amtrak

4/55,440 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5440 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $87

Greyhound Louisville Chicago recent customer reviews

The bus was 30 minutes late, there were too many people on board, leaving a couple to stand. Then the driver had to slam on his brakes and I don’t know how the standing people didn’t get thrown up front. At one point the driver was getting on the interstate going the wrong way, until people started yelling at him. Absolutely not the best ride.

Reese W.

October 25, 2023

Mobile chargers and WiFi was not working at all despite the fact that same were informed to be working conditions

Muhammad Amir B.

February 6, 2020

I had a stop over at Indianapolis, IN.of supposedly for 30min.on my way to Chgo.but somehow the mgr said the bus to Chgo.was delayed for 1hr coming from Cincinnati then later on the driver of my bus said that it's not delayed and it's leaving! I almost miss my bus! So much confusion! Why can't they get their schedule right! Also the toilet on the bus has no more toilet paper plus it's too dark in there. I will never take this bus again! This was my first experience (in a very long time )and my last! Pls get your schedules right!

Phoebe T.

November 3, 2019

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Louisville to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Louisville to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Louisville to Chicago.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from Louisville, we help you find what you're looking for based on how much of a budget you have.

Where are the popular stops in Louisville and Chicago?

Stops in Louisville

A - Louisville Greyhound Bus Station

Stops in Chicago

A - Downtown Greyhound Station

B - Chicago O'Hare International Airport

C - Polk St & Canal St

D - Tornado Bus S Kedzie Ave

E - Cumberland CTA

F - Turimex California Ave

Frequently asked questions for your trip Louisville - Chicago

What is the travel distance from Louisville to Chicago?
What are the departure and arrival stations when taking the bus from Louisville to Chicago?
What are the best sights and things to do in Chicago?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/31

No data

09/01

$62

Today

$60

09/03

$40

09/04

No data

09/05

$43

09/06

$41

09/07

$37

The cheapest trip from Louisville to Chicago was searched and found on Sep 7, 2025 with a price of $37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago, as early as possible.

You can expect to pay from $37 to $151 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $37 which is on 2025-09-07.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Louisville to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Louisville to Chicago.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Louisville to Chicago.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Louisville to Chicago.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Louisville by bus?

Bus from Chicago to Louisville

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Louisville to Chicago

Cheap buses leaving Friday

One passenger / one way

Bus Louisville to Chicago: Trip Overview

Compare bus companies

Greyhound Louisville Chicago recent customer reviews

Greyhound Louisville Chicago recent customer reviews

Greyhound Louisville Chicago recent customer reviews

Louisville to Chicago Bus

Where are the popular stops in Louisville and Chicago?

Frequently asked questions for your trip Louisville - Chicago

What is the travel distance from Louisville to Chicago?

What are the departure and arrival stations when taking the bus from Louisville to Chicago?

What are the best sights and things to do in Chicago?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

Will you be returning to Louisville by bus?

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Louisville

Buses Leaving from Louisville

Buses Going to Louisville

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago

Popular routes in this country

Popular airport transfers