Bus Tickets from Portland, OR to Louisville

Find affordable bus tickets from Portland, OR to Louisville with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen trips

One passenger / one way

  • Departure time: September 6 at
    Departure city: Portland
    Departure location: Portland Union Station
    Arrival time: September 9 at
    Destination city: Louisville
    Destination location: Louisville, KY
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 15 at
    Departure city: Portland
    Departure location: Portland Union Station
    Arrival time: September 19 at
    Destination city: Louisville
    Destination location: Louisville Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 20 at
    Departure city: Portland
    Departure location: Portland Union Station
    Arrival time: September 24 at
    Destination city: Louisville
    Destination location: Louisville, KY
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: January 4 at
    Departure city: Portland
    Departure location: Portland Union Station
    Arrival time: January 8 at
    Destination city: Louisville
    Destination location: Louisville, KY
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: February 18 at
    Departure city: Portland
    Departure location: Portland Union Station
    Arrival time: February 22 at
    Destination city: Louisville
    Destination location: Louisville, KY
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Portland to Louisville.

Bus
Average Price$240 - $413Average Duration2d 17h
78kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$317 - $442Average Duration2d 9h
285kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Portland to Louisville

Among the sustainable travel choices, the bus stands out as the good way to reach Louisville. The journey takes about 2 days, 17 hours and with fares starting at just $240, it presents an excellent value for a comfortable ride.

2bus per day
2d 17hAverage Duration
$240Cheapest ticket
78kgCO₂ emissions

Bus Portland, OR to Louisville: Trip Overview

Average ticket price$276
Average bus trip duration2d 17h
Number of daily buses2
Earliest bus departure2:00am
Distance1941 miles (3130 km)
Latest bus departure8:00pm

Portland to Louisville Bus

With Busbud, comparing and booking tickets for a bus from Portland to Louisville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Portland to Louisville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Louisville from Portland, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Portland, OR - Louisville

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/27
No data
08/28
No data
Today
No data
08/30
$247
08/31
No data
09/01
$245
09/02
$233
09/03
No data
busbud logoThe cheapest trip from Portland, OR to Louisville was searched and found on Sep 2, 2025 with a price of $233

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, OR to Louisville, as early as possible.

You can expect to pay from $233 to $3,513 for a bus ticket from Portland, OR to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $233 which is on 2025-09-02.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Portland to Louisville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Portland to Louisville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Portland to Louisville.

Make a music playlist for your bus ride from Portland to Louisville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Portland, OR to Louisville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Portland, OR by bus?

Bus from Louisville to Portland, OR

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Portland

Buses Leaving from Portland

Buses Going to Portland

Popular Buses Connecting Louisville

Buses Leaving from Louisville

Buses Going to Louisville