Bus Tickets from Chicago to Louisville

Next departures

Next departures for Chicago to Louisville on September 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Chicago 95Th & Dan Ryan
Louisville, KYCheapest
FlixBus
Chicago 95Th & Dan Ryan
Louisville, KYFastest
Greyhound Lines, Inc.
Downtown Greyhound Station
Louisville, KYNo tags
FlixBus
Downtown Greyhound Station
Louisville, KYNo tags
FlixBus + Greyhound Lines, Inc.
Chicago 95Th & Dan Ryan
Louisville, KYNo tags

Accepted payments

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Compare 2 ways to go from Chicago to Louisville.

Bus
Average Price$36 - $163Average Duration6h 50m
10kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$77 - $116Average Duration10h 35m
39kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Chicago to Louisville

Among the sustainable travel choices, the bus stands out as the good way to reach Louisville. The journey takes about 6 hours 50 minutes and with fares starting at just $36, it presents an excellent value for a comfortable ride.

17bus per day
6h 50mAverage Duration
$36Cheapest ticket
10kgCO₂ emissions

Bus Chicago to Louisville: Trip Overview

Average ticket price$60
Average bus trip duration6h 50m
Number of daily buses17
Earliest bus departure12:30am
Distance259 miles (417 km)
Latest bus departure11:59pm

Chicago to Louisville Bus

With Busbud, comparing and booking tickets for a bus from Chicago to Louisville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Chicago to Louisville from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Chicago to Louisville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Chicago - Louisville

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/31
No data
09/01
$47
Today
$55
09/03
No data
09/04
$33
09/05
$41
09/06
No data
09/07
No data
busbud logoThe cheapest trip from Chicago to Louisville was searched and found on Sep 4, 2025 with a price of $33

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Louisville, as early as possible.

You can expect to pay from $33 to $155 for a bus ticket from Chicago to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $33 which is on 2025-09-04.

Usually Amtrak, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Chicago to Louisville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to Louisville, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to Louisville that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Chicago to Louisville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Chicago to Louisville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Chicago by bus?

Bus from Louisville to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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