Bus Tickets from Los Angeles to Santiago

Find affordable bus tickets from Los Angeles to Santiago with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 14
from $11
TomorrowMay 15
from $12
FriMay 16
from $13
SatMay 17
from $13
SunMay 18
from $13
MonMay 19
from $13
TueMay 20
WedMay 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 15 at
    Departure city: Los Angeles
    Departure location: 1890 Avenida Sor Vicenta
    Arrival time: May 15 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 15 at
    Departure city: Los Angeles
    Departure location: 1890 Avenida Sor Vicenta
    Arrival time: May 15 at
    Destination city: Santiago
    Destination location: Terminal Los Héroes
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: Los Angeles
    Departure location: 1890 Avenida Sor Vicenta
    Arrival time: May 15 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: Buses TranSantinBuses TranSantin
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: Los Angeles
    Departure location: 1890 Avenida Sor Vicenta
    Arrival time: May 16 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: Los Angeles
    Departure location: Terminal de Buses de Los Angeles
    Arrival time: May 16 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: Pullman TurPullman Tur
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Los Angeles to Santiago: Trip Overview

Average ticket price$18
Average bus trip duration5h 22m
Number of daily buses33
Earliest bus departure12:10am
Distance291 miles (469 km)
Latest bus departure11:59pm

Los Angeles to Santiago Bus

With Busbud, comparing and booking tickets for a bus from Los Angeles to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Los Angeles to Santiago will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Los Angeles to Santiago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Los Angeles - Santiago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/12
$13
05/13
$12
Today
$11
05/15
$12
05/16
$13
05/17
$13
05/18
$13
05/19
$13
busbud logoThe cheapest trip from Los Angeles to Santiago was searched and found on May 14, 2025 with a price of $11

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Los Angeles to Santiago, as early as possible.

You can expect to pay from $11 to $30 for a bus ticket from Los Angeles to Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at $12 which is on 2025-05-15.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Los Angeles to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Los Angeles to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Los Angeles to Santiago that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Los Angeles to Santiago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Los Angeles by bus?

Bus from Los Angeles to Santiago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Los Angeles

Buses Leaving from Los Angeles

Buses Going to Los Angeles

Popular Buses Connecting Santiago

Buses Leaving from Santiago

Buses Going to Santiago