Bus Tickets from Lake City to Knoxville, TN

Bus Lake City to Knoxville, TN: Trip Overview

Average ticket price$64
Average bus trip duration12h 15m
Number of daily buses1
Earliest bus departure9:35am
Distance407 miles (656 km)

Lake City to Knoxville Bus

With Busbud, comparing and booking tickets for a bus from Lake City to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Lake City to Knoxville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Lake City to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Lake City - Knoxville, TN

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/30
No data
08/31
No data
Today
No data
09/02
No data
09/03
No data
09/04
No data
09/05
No data
09/06
$56
busbud logoThe cheapest trip from Lake City to Knoxville, TN was searched and found on Sep 6, 2025 with a price of $56

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lake City to Knoxville, TN, as early as possible.

You can expect to pay from $56 to $56 for a bus ticket from Lake City to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $56 which is on 2025-09-06.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Lake City to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lake City to Knoxville, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lake City to Knoxville will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Lake City to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Lake City by bus?

Bus from Knoxville, TN to Lake City

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Lake City

Buses Leaving from Lake City

Buses Going to Lake City

Popular Buses Connecting Knoxville

Buses Leaving from Knoxville

Buses Going to Knoxville