Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Knoxville Bus Station | Houston Bus Station | Cheapest | |||||
Greyhound Lines, Inc. + FlixBus | Knoxville Bus Station | The Woodlands - Windvale Center | Fastest | |||||
| Knoxville Bus Station | Houston Bus Station | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Knoxville Bus Station | Downtown Gray & Smith | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Knoxville Bus Station | Downtown Gray & Smith | No tags |
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Bus Knoxville, TN to Houston, US: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Knoxville Houston recent customer reviews
Got into Atlanta and bus was cancelled set there 22hrs before rerouted on another trip. First time using a bus for travel and will be the last time
Rachelle N.
Facilities were very dirty and passengers were not respectful to the rules. I feel as if the bus should be monitored by one of the greyhound employees while the other is driving. Staff was not very friendly but instead always in a rush.
Louana W.
Was ok but not the best
Anthony F.
Knoxville to Houston Bus
Busbud helps you find a bus from Knoxville to Houston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Houston.
From cheap bus tickets to more luxurious buses traveling from Knoxville to Houston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Knoxville and Houston?
Frequently asked questions for your trip Knoxville, TN - Houston, US
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Houston, US was searched and found on Aug 31, 2025 with a price of $102To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Houston, US, as early as possible.
You can expect to pay from $102 to $199 for a bus ticket from Knoxville, TN to Houston, US based on the last 2 days. You can expect to find the cheapest price for the trip at $103 which is on 2025-09-04.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Knoxville and Houston!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Knoxville to Houston.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Knoxville to Houston that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Houston.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Top traveled bus routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Orlando
- Bus from Knoxville to Lexington
- Bus Knoxville - Chicago
- Knoxville - Miami
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - Memphis
- Bus from Knoxville to New York City
- Bus Knoxville - Washington
- Knoxville - Asheville
- Bus from Knoxville to Jackson
- Bus Knoxville - Cincinnati
- Knoxville - Roanoke
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Asheville - Knoxville
- New York City - Knoxville
- Bus from Greenville to Knoxville
- Bus Louisville - Knoxville
- Lexington - Knoxville
- Bus from Cookeville to Knoxville
- Bus Dallas - Knoxville
- Dayton - Knoxville
Popular Buses Connecting Houston
Buses Leaving from Houston
- Bus from Houston to Lamar
- Bus Houston - Marathon
- Houston - Pompano Beach
- Bus from Houston to Austin
- Bus Houston - Orlando
- Houston - Hamilton
- Bus from Houston to New Orleans
- Bus Houston - Fort Worth
- Houston - Atlanta
- Bus from Houston to New York City
- Bus Houston - College Station
- Houston - Miami
- Bus from Houston to McAllen
- Bus Houston - Little Rock
- Houston - Chicago
Buses Going to Houston
- Bus from Katy to Houston
- Bus Atlanta - Houston
- Cypress - Houston
- Bus from New Orleans to Houston
- Bus Sunnyside - Houston
- Denver - Houston
- Bus from Fort Worth to Houston
- Bus New York City - Houston
- McAllen - Houston
- Bus from Laredo to Houston
- Bus San Marcos - Houston
- El Paso - Houston
- Bus from Baton Rouge to Houston
- Bus Frisco - Houston
- College Station - Houston
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Miami - Tampa
- Bus from Seattle to Leavenworth
- Bus Austin - Dallas
- Dallas - Austin
- Bus from Houston to San Antonio
- Bus Austin - Houston
- Orlando - Atlanta
- Bus from New York City to Los Angeles
- Bus Dallas - San Antonio
- San Antonio - Houston