Bus Tickets from Houston, US to Knoxville (TN)

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FriJun 13
SatJun 14
SunJun 15
MonJun 16
TueJun 17
WedJun 18
from $147
ThuJun 19
FriJun 20

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 18 at
    Departure city: Houston
    Departure location: Hillcroft Ave & Southwest Freeway
    Arrival time: June 19 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Valley Transit + Greyhound Lines, Inc.
    Valley Transit + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 18 at
    Departure city: Houston
    Departure location: Houston Bus Station
    Arrival time: June 19 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 18 at
    Departure city: Houston
    Departure location: Houston Bus Station
    Arrival time: June 19 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 18 at
    Departure city: Houston
    Departure location: Downtown Gray & Smith
    Arrival time: June 19 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Valley Transit + Greyhound Lines, Inc.
    FlixBus + Valley Transit + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 18 at
    Departure city: Houston
    Departure location: Houston Uptown/Upper Kirby
    Arrival time: June 19 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Houston to Knoxville: Trip Overview

Average ticket price$151
Average bus trip duration1d 7h
Number of daily buses7
Earliest bus departure6:35am
Distance790 miles (1273 km)
Latest bus departure10:00pm

Houston to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Houston to Knoxville.

Bus service from Houston to Knoxville will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Houston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Houston, US - Knoxville (TN)

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/09
$126
06/10
No data
Today
No data
06/12
No data
06/13
No data
06/14
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06/15
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06/16
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busbud logoThe cheapest trip from Houston to Knoxville was searched and found on Jun 9, 2025 with a price of $126

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston to Knoxville, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Houston to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Houston to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Houston to Knoxville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Houston to Knoxville.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Houston by bus?

Bus from Houston to Knoxville

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