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| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Knoxville Bus Station | 4565 Gaynor Ave, North Charleston | CheapestFastest |
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Bus Knoxville, TN to Charleston, SC, US: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Knoxville to Charleston Bus
With Busbud, comparing and booking tickets for a bus from Knoxville to Charleston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Knoxville to Charleston will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from Knoxville to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Knoxville and Charleston?
Frequently asked questions for your trip Knoxville, TN - Charleston, SC, US
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Knoxville to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Knoxville to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Knoxville to Charleston that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Knoxville to Charleston while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top traveled bus routes
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Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Orlando
- Bus from Knoxville to Lexington
- Bus Knoxville - Chicago
- Knoxville - Greenville
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - New York City
- Bus from Knoxville to Memphis
- Bus Knoxville - Washington
- Knoxville - Asheville
- Bus from Knoxville to Miami
- Bus Knoxville - Jackson
- Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Asheville - Knoxville
- New York City - Knoxville
- Bus from Greenville to Knoxville
- Bus Louisville - Knoxville
- Cookeville - Knoxville
- Bus from Lexington to Knoxville
- Bus Dallas - Knoxville
- Dayton - Knoxville
Popular Buses Connecting Charleston
Buses Leaving from Charleston
- Bus from Charleston to Baltimore
- Bus Charleston - Tulsa
- Charleston - Atlanta
- Bus from Charleston to Fort Worth
- Bus Charleston - Miami
- Charleston - Jacksonville
- Bus from Charleston to Savannah
- Bus Charleston - Greenville
- Charleston - Charlotte
- Bus from Charleston to Orlando
- Bus Charleston - New York City
- Charleston - Florence
- Bus from Charleston to Raleigh
- Bus Charleston - Wilmington
- Charleston - Washington
Buses Going to Charleston
- Bus from Baltimore to Charleston
- Bus Boston - Charleston
- Greenville - Charleston
- Bus from Greenville to Charleston
- Bus Raleigh - Charleston
- Nashville - Charleston
- Bus from Savannah to Charleston
- Bus Atlanta - Charleston
- Orlando - Charleston
- Bus from New York City to Charleston
- Bus Charlotte - Charleston
- Miami - Charleston
- Bus from Jacksonville to Charleston
- Bus Washington - Charleston
- Tampa - Charleston