Bus Tickets from Greenville, SC to Pittsburgh

Next departures

Next departures for Greenville to Pittsburgh on September 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
Pittsburgh Intermodal StationCheapest
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
Pittsburgh Intermodal StationFastest
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
Pittsburgh Intermodal StationNo tags
FlixBus
1116 Woodruff Rd
Pittsburgh Intermodal StationNo tags

Accepted payments

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Compare 2 ways to go from Greenville to Pittsburgh.

Bus
Average Price$88 - $199Average Duration17h 15m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$152 - $316Average Duration21h 17m
60kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Pittsburgh

Among the sustainable travel choices, the bus stands out as the good way to reach Pittsburgh. The journey takes about 17 hours 15 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.

3bus per day
17h 15mAverage Duration
$88Cheapest ticket
16kgCO₂ emissions

Bus Greenville, SC to Pittsburgh: Trip Overview

Average ticket price$122
Average bus trip duration17h 15m
Number of daily buses3
Earliest bus departure10:50am
Distance408 miles (657 km)
Latest bus departure10:00pm

Greenville to Pittsburgh Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Greenville to Pittsburgh.

We make sure you can find a bus service from Greenville to Pittsburgh from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Pittsburgh will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Greenville, SC - Pittsburgh

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/31
No data
09/01
No data
Today
$94
09/03
No data
09/04
$102
09/05
No data
09/06
No data
09/07
No data
busbud logoThe cheapest trip from Greenville, SC to Pittsburgh was searched and found on Sep 2, 2025 with a price of $94

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Pittsburgh, as early as possible.

You can expect to pay from $94 to $122 for a bus ticket from Greenville, SC to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $102 which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Greenville to Pittsburgh but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Pittsburgh, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Pittsburgh will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Pittsburgh.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Greenville, SC to Pittsburgh?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Pittsburgh to Greenville, SC

You can also go to Pittsburgh by train

Train from Greenville, SC to Pittsburgh

Why choose Busbud?

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