Bus Tickets from Greenville (SC) to Pittsburgh

Find affordable bus tickets from Greenville (SC) to Pittsburgh with flexible options. Book your trip now

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TodayJun 11
from US$161
TomorrowJun 12
FriJun 13
from US$178
SatJun 14
SunJun 15
from US$182
MonJun 16
from US$98
TueJun 17
from US$92
WedJun 18

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 13 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 14 at
    Destination city: Pittsburgh
    Destination location: Pittsburgh Intermodal Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 13 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 14 at
    Destination city: Pittsburgh
    Destination location: Pittsburgh Intermodal Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 13 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 14 at
    Destination city: Pittsburgh
    Destination location: Pittsburgh Intermodal Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 13 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 14 at
    Destination city: Pittsburgh
    Destination location: Pittsburgh Intermodal Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Friday at 6:22 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Greenville to Pittsburgh

Bus
Average PriceUS$70 - US$225Average Duration20h 25m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$244 - US$405Average Duration21h 25m
60kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Pittsburgh

Among the sustainable travel choices, the bus stands out as a good way to reach Pittsburgh. The journey takes about 20 hours 25 minutes, and with fares starting at just US$70, it presents an excellent value for a comfortable ride.

3bus per day
20h 25mAverage Duration
US$70Cheapest ticket
16kgCO₂ emissions

Bus Greenville to Pittsburgh: Trip Overview

Average Ticket PriceUS$163
Average Bus Trip Duration20h 25m
Number of daily buses3
Earliest bus departure10:50am
Distance657 km
Latest bus departure10:00pm

Greenville to Pittsburgh Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Greenville to Pittsburgh.

We make sure you can find a bus service from Greenville to Pittsburgh from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Pittsburgh will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville (SC) - Pittsburgh

  1. How long does it take to get to Pittsburgh from Greenville by bus?

    The trip from Greenville to Pittsburgh will take on average 20h 25m. For the shortest travel time, select the fastest bus available, which will take you to Pittsburgh in about 18h 25m.

  2. What is the distance between Greenville and Pittsburgh?

    The distance between Greenville and Pittsburgh is approximately 657 km (408 miles).

  3. What are the departure and arrival locations for buses traveling from Greenville to Pittsburgh?

    Buses departing from Guadalajara Supermarket Bus Stop in Greenville will take you to Intermodal Station in Pittsburgh.

  4. What is the cheapest way to travel from Greenville to Pittsburgh?

    The least expensive option to go from Greenville to Pittsburgh would be going by bus. The ticket price for this bus starts at US$70, making this your best choice for this trip.

  5. How much is the bus from Greenville to Pittsburgh?

    You can expect to pay around US$163 for the bus ride from Greenville to Pittsburgh.

  6. Is it possible to travel by overnight bus from Greenville to Pittsburgh?

    Yes! If you're heading from Greenville to Pittsburgh, you'll find buses departing until 10:00pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-09
No data
06-10
US$177
Today
US$153
06-12
No data
06-13
No data
06-14
No data
06-15
No data
06-16
No data
busbud logoThe cheapest trip from Greenville to Pittsburgh was searched and found on Jun 11, 2025 with a price of US$153

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Pittsburgh, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Greenville to Pittsburgh but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Pittsburgh, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Pittsburgh will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Pittsburgh.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Greenville to Pittsburgh?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville by bus?

Bus from Greenville to Pittsburgh

You can also go to Pittsburgh by train

Train from Greenville to Pittsburgh

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