Bus Tickets from Greenville, SC to Philadelphia, PA

Next departures

Next departures for Greenville to Philadelphia on September 25
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
1116 Woodruff Rd
Cherry Hill MallCheapest
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
199 Spring Garden St.Fastest
Greyhound Lines, Inc.
1116 Woodruff Rd
199 Spring Garden St.No tags
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
199 Spring Garden St.No tags
FlixBus
1116 Woodruff Rd
Philadelphia, 199 Spring Garden StNo tags

Last refresh of the prices: Yesterday at 8:02 PM EDT.

Accepted payments

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  • China Union Pay
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  • JCB payment
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Compare 2 ways to go from Greenville to Philadelphia.

Bus
Average Price$62 - $163Average Duration18h 5m
21kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$128 - $320Average Duration14h 45m
78kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Greenville to Philadelphia

Among the sustainable travel choices, the bus stands out as the good way to reach Philadelphia. The journey takes about 18 hours 5 minutes and with fares starting at just $62, it presents an excellent value for a comfortable ride.

19bus per day
18h 5mAverage Duration
$62Cheapest ticket
21kgCO₂ emissions

Bus Greenville, SC to Philadelphia, PA: Trip Overview

Average ticket price$93
Average bus trip duration18h 5m
Number of daily buses19
Earliest bus departure7:25am
Distance518 miles (834 km)
Latest bus departure10:00pm

Greenville to Philadelphia Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Philadelphia is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Greenville to Philadelphia from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Philadelphia will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Greenville, SC - Philadelphia, PA

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/22
$129
09/23
$91
Today
$95
09/25
$57
09/26
$89
09/27
$81
09/28
$75
09/29
$85
busbud logoThe cheapest trip from Greenville, SC to Philadelphia, PA was searched and found on Sep 25, 2025 with a price of $57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Philadelphia, PA, as early as possible.

You can expect to pay from $57 to $152 for a bus ticket from Greenville, SC to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $57 which is on 2025-09-25.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Greenville to Philadelphia.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Philadelphia, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Philadelphia will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Philadelphia while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Greenville, SC to Philadelphia, PA?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Philadelphia, PA to Greenville, SC

You can also go to Philadelphia, PA by train

Train from Greenville, SC to Philadelphia, PA

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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