Bus Tickets from Gainesville, GA to Greenville, SC

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TodaySep 2
TomorrowSep 3
ThuSep 4
FriSep 5
from $41
SatSep 6
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MonSep 8
TueSep 9

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: September 5 at
    Departure city: Gainesville
    Departure location: Gainesville (Mart 24/7)
    Arrival time: September 6 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: September 5 at
    Departure city: Gainesville
    Departure location: Gainesville, (GA - BBWireless)
    Arrival time: September 5 at
    Destination city: Greenville
    Destination location: Greenville, (SC - Taqueria Guadalajara #3)
    Operated by: ExpresoExpreso
    Vehicle: BusDuration:
  • Departure time: September 5 at
    Departure city: Gainesville
    Departure location: Gainesville, (GA - BBWireless)
    Arrival time: September 5 at
    Destination city: Greenville
    Destination location: Greenville, (SC - Taqueria Guadalajara #3)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: September 5 at
    Departure city: Gainesville
    Departure location: Gainesville, (GA - BBWireless)
    Arrival time: September 5 at
    Destination city: Greenville
    Destination location: Greenville, (SC - Taqueria Guadalajara #3)
    Operated by: ExpresoExpreso
    Vehicle: BusDuration:
  • Departure time: September 5 at
    Departure city: Gainesville
    Departure location: Gainesville, (GA - BBWireless)
    Arrival time: September 7 at
    Destination city: Greenville
    Destination location: Greenville, (SC - Taqueria Guadalajara #3)
    Operated by: Expreso + Tornado Bus
    Expreso + Tornado Bus
    Vehicle: BusDuration:

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Compare 2 ways to go from Gainesville to Greenville.

Bus
Average Price$36 - $101Average Duration2h 30m
4kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$36 - $81Average Duration1h 54m
13kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Gainesville to Greenville

Among the sustainable travel choices, the train stands out as the good way to reach Greenville. The journey takes about 1 hour 54 minutes and with fares starting at just $36, it presents an excellent value for a comfortable ride.

1train per day
1h 54mAverage Duration
$36Cheapest ticket
13kgCO₂ emissions

Bus Gainesville, GA to Greenville, SC: Trip Overview

Average ticket price$101
Average bus trip duration2h 30m
Number of daily buses3
Earliest bus departure9:59am
Distance88 miles (141 km)
Latest bus departure10:20pm

Gainesville to Greenville Bus

With Busbud, comparing and booking tickets for a bus from Gainesville to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Gainesville to Greenville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Gainesville to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Gainesville, GA - Greenville, SC

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/31
No data
09/01
$47
Today
No data
09/03
No data
09/04
No data
09/05
$34
09/06
$29
09/07
$35
busbud logoThe cheapest trip from Gainesville, GA to Greenville, SC was searched and found on Sep 6, 2025 with a price of $29

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, GA to Greenville, SC, as early as possible.

You can expect to pay from $29 to $95 for a bus ticket from Gainesville, GA to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $29 which is on 2025-09-06.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Gainesville to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Gainesville to Greenville, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Gainesville to Greenville will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Gainesville to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Will you be returning to Gainesville, GA by bus?

Bus from Greenville, SC to Gainesville, GA

You can also go to Greenville, SC by train

Train from Gainesville, GA to Greenville, SC

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