Bus Tickets from Charleston, WV, US to Knoxville, TN

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TodaySep 1
TomorrowSep 2
from $69
WedSep 3
ThuSep 4
FriSep 5
from $45
SatSep 6
SunSep 7
MonSep 8

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: September 2 at
    Departure city: Charleston
    Departure location: Charleston Bus Station
    Arrival time: September 2 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Charleston, WV, US to Knoxville, TN: Trip Overview

Average ticket price$54
Average bus trip duration12h 50m
Number of daily buses1
Earliest bus departure5:15am
Distance204 miles (329 km)

Charleston to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Charleston to Knoxville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Charleston to Knoxville.

From cheap bus tickets to more luxurious buses traveling from Charleston to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Charleston, WV, US - Knoxville, TN

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/30
$46
08/31
No data
Today
$55
09/02
$61
09/03
No data
09/04
No data
09/05
$37
09/06
No data
busbud logoThe cheapest trip from Charleston, WV, US to Knoxville, TN was searched and found on Sep 5, 2025 with a price of $37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, WV, US to Knoxville, TN, as early as possible.

You can expect to pay from $37 to $61 for a bus ticket from Charleston, WV, US to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $37 which is on 2025-09-05.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Charleston to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Charleston to Knoxville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Charleston to Knoxville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Charleston to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

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