Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Madrid (South) | Santander (Estacion de Autobuses) | CheapestFastest |
Last refresh of the prices: Today at 09:57 CET.
Compare 3 ways to travel from Madrid to Santander
Among the sustainable travel choices, the Carpool stands out as a good way to reach Santander. The journey takes about 4 hours 30 minutes and with fares starting at just £16, it presents an excellent value for a comfortable ride.
Where are the popular stops in Madrid and Santander?
Stops in Madrid
- BAvenida de América, 9, 28002 Madrid, Spain
- CMendez Alvaro, 83, , Madrid, 28045, Spain
- DPlaza Moncloa, 671, 28008 Madrid, Spain
- E
Madrid Interc. Plaza Castilla
Madrid Interc. Plaza Castilla, 28046 Madrid, Spain - FMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
Stops in Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
- C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
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Frequently asked questions about travelling by bus from Madrid to Santander
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Madrid to Santander?
The cheapest coach tickets from Madrid to Santander start from £37. The average price for this route is around £41. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Madrid to Santander?
The average bus journey time from Madrid to Santander is 5h 30m, covering a distance of 205 miles. The fastest bus can take you there in 4h 25m and is operated by ALSA.
Which bus companies service the Madrid to Santander route?
What is the earliest and latest departure time for the bus from Madrid to Santander?
The earliest bus departs from Madrid to Santander at 00:30. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from Madrid to Santander?
A bus journey from Madrid to Santander produces an estimated 8 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Madrid to Santander?
According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61149 reviews.
Which company has the best Wi-Fi from Madrid to Santander?
Based on Busbud reviews, the bus company ALSA has the best Wi-Fi rating with a score of 3.5.
Which bus company offers the most punctual service from Madrid to Santander?
According to Busbud traveller reviews, the most punctual bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Madrid to Santander?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Madrid to Santander was searched and found on 27 Jan 2026 with a price of £32To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Santander as early as possible.
You can expect to pay from £32 to £50 for a bus ticket from Madrid to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at £32, which is on 2026-01-27.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
