Bus Tickets from Madrid to Santander

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Next departures

Next departures for Madrid to Santander on September 17
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ALSA
Avenida de América Metro
Santander (Estacion de Autobuses)Cheapest
ALSA
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)Fastest
ALSA Supra
Avenida de América Metro
Santander (Estacion de Autobuses)No tags
Flixbus
Madrid (South)
Santander (Estacion de Autobuses)No tags
ALSA Supra
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)No tags

Accepted payments

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Compare 3 ways to go from Madrid to Santander

Bus
Average PriceUS$52 - US$167Average Duration5h 30m
8kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average PriceUS$38 - US$97Average Duration4h 21m
8kg CO₂e5 out of 5 stars
Fastest
Carpool
Average PriceUS$19 - US$58Average Duration4h 30m
14kg CO₂e4 out of 5 stars
Cheapest
busbud logoBusbud recommends carpooling from Madrid to Santander

Among the sustainable travel choices, the carpool stands out as a good way to reach Santander. The journey takes about 4 hours 30 minutes, and with fares starting at just US$19, it presents an excellent value for a comfortable ride.

29carpool per day
4h 30mAverage Duration
US$19Cheapest ticket
14kgCO₂ emissions

Bus Madrid to Santander: Trip Overview

Average Ticket PriceUS$54
Average Bus Trip Duration5h 30m
Number of daily buses13
Earliest bus departure12:30am
Distance330 km
Latest bus departure11:45pm

Madrid to Santander Bus

With Busbud, comparing and booking tickets for a bus from Madrid to Santander is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Madrid to Santander.

Discover how much the bus trip from Madrid to Santander will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Madrid - Santander

  1. How far is Madrid from Santander?

    Madrid and Santander are 340 km (211 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Madrid to Santander?

    Buses departing from Avenida de América Metro in Madrid will take you to Calle Navas de Tolosa, 2 in Santander.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-14
US$48
09-15
US$178
Today
US$76
09-17
US$40
09-18
US$40
09-19
US$49
09-20
US$40
09-21
US$47
busbud logoThe cheapest trip from Madrid to Santander was searched and found on Sep 17, 2025 with a price of US$40

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Santander, as early as possible.

You can expect to pay from US$40 to US$178 for a bus ticket from Madrid to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at US$40 which is on 2025-09-17.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Madrid to Santander.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Madrid to Santander.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Madrid to Santander will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Madrid to Santander.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Madrid by bus?

Bus from Santander to Madrid

You can also go to Santander by train

Train from Madrid to Santander

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