Bus Tickets from Santander to Madrid

Next departures

Next departures for Santander to Madrid on September 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ALSA
Santander (Estacion de Autobuses)
Avenida de América MetroCheapest
ALSA Supra
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4Fastest
ALSA Supra
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4No tags
ALSA
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4No tags
Flixbus
Santander (Estacion de Autobuses)
Madrid (South)No tags

Accepted payments

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Compare 3 ways to go from Santander to Madrid

Bus
Average PriceUS$44 - US$206Average Duration5h 40m
8kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average PriceUS$32 - US$96Average Duration4h 16m
8kg CO₂e5 out of 5 stars
Fastest
Carpool
Average PriceUS$17 - US$55Average Duration4h 30m
14kg CO₂e4 out of 5 stars
Cheapest
busbud logoBusbud recommends carpooling from Santander to Madrid

Among the sustainable travel choices, the carpool stands out as a good way to reach Madrid. The journey takes about 4 hours 30 minutes, and with fares starting at just US$17, it presents an excellent value for a comfortable ride.

34carpool per day
4h 30mAverage Duration
US$17Cheapest ticket
14kgCO₂ emissions

Bus Santander to Madrid: Trip Overview

Average Ticket PriceUS$54
Average Bus Trip Duration5h 40m
Number of daily buses13
Earliest bus departure12:45am
Distance336 km
Latest bus departure7:30pm

Santander to Madrid Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santander to Madrid.

We make it our job to connect you with the most dependable bus companies that cover bus service from Santander to Madrid.

Discover how much the bus trip from Santander to Madrid will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Santander - Madrid

  1. What is the travel distance from Santander to Madrid?

    The distance between Santander and Madrid is around 340 km (211 miles).

  2. What are the departure and arrival locations for buses traveling from Santander to Madrid?

    Buses traveling this route start their trip at Calle Navas de Tolosa, 2, in Santander, and end it at Madrid-Barajas Airport, in Madrid.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-01
US$147
09-02
US$163
Today
US$38
09-04
US$38
09-05
US$38
09-06
US$38
09-07
US$38
09-08
US$40
busbud logoThe cheapest trip from Santander to Madrid was searched and found on Sep 4, 2025 with a price of US$38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Madrid, as early as possible.

You can expect to pay from US$38 to US$163 for a bus ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at US$38 which is on 2025-09-04.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santander to Madrid but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Santander to Madrid.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santander to Madrid will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Santander to Madrid, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Santander by bus?

Bus from Madrid to Santander

You can also go to Madrid by train

Train from Santander to Madrid

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