Train from Santander to Madrid: Tickets & Schedules

Next train departures

Next departures for Santander to Madrid on March 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
RENFE AlviaTrain
Santander
Madrid-ChamartinCheapestFastest
RENFE AlviaTrain
Santander
Madrid-ChamartinNo tags
RENFE AlviaTrain
Santander
Madrid-ChamartinNo tags
RENFE AlviaTrain
Santander
Madrid-ChamartinNo tags

Last refresh of the prices: Today at 4:14 AM CET.

Compare 2 ways to go from Santander to Madrid

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Madrid. The journey takes about 4 hours 23 minutes, and with fares starting at just $37, it presents an excellent value for a comfortable ride.

2train per day
4h 23mAverage Duration
333 kmDistance
8kgCO₂ emissions
Average Price$67 - $246Average Duration5h 30m
8kg CO₂e
Average Price$37 - $127Average Duration4h 23m
8kg CO₂e

Frequently asked questions about travelling from Santander to Madrid by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Santander to Madrid?

    The cheapest train tickets from Santander to Madrid start at $37. The average price for this train route is around $56. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.

  2. Which train operators serve the Santander to Madrid route?

    Several major train operators serve this route, with 2 trains available per day.

  3. What are the earliest and latest departure times for the train from Santander to Madrid?

    The earliest train from Santander to Madrid departs at 1:58pm. The latest train departs at 7:00pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03-23
$40
03-24
$40
Today
$40
03-26
$40
03-27
$40
03-28
$50
03-29
$51
03-30
$40
busbud logoThe cheapest trip from Santander to Madrid was searched and found on Mar 26, 2026 with a price of $40

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Santander to Madrid, as early as possible.

You can expect to pay from $40 to $93 for a train ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at $40 which is on 2026-03-26.

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