Find coaches from Winston-Salem to Indianapolis

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Next departures

Next departures from Winston-Salem to Indianapolis on 24 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Winston Salem Greyhound Bus Station
Indianapolis Bus StationCheapestFastest
Greyhound Lines, Inc.
Winston Salem Greyhound Bus Station
Indianapolis Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Winston Salem Greyhound Bus Station
Downtown Transit CenterNo tags
Greyhound Lines, Inc.
Winston Salem Greyhound Bus Station
Indianapolis Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Winston Salem Greyhound Bus Station
Downtown Transit CenterNo tags

Accepted payments

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Bus Winston-Salem to Indianapolis: Trip Overview

Average ticket priceUS$117
Average bus trip duration22h 20m
Number of daily buses6
Earliest bus departure06:55
Distance409 miles
Latest bus departure18:15

Winston-Salem to Indianapolis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Winston-Salem to Indianapolis.

Bus service from Winston-Salem to Indianapolis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from Winston-Salem, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Winston-Salem - Indianapolis

  1. What's the distance between Winston-Salem and Indianapolis by coach?

    The distance between Winston-Salem and Indianapolis by coach is approximately 410 miles (661 km).

  2. How can I travel from Winston-Salem to Indianapolis avoiding air travel?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
16/09
No data
17/09
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Today
US$78
19/09
No data
20/09
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21/09
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22/09
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23/09
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busbud logoThe cheapest trip from Winston-Salem to Indianapolis was searched and found on 18 Sept 2025 with a price of US$78

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Indianapolis as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Winston-Salem to Indianapolis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Winston-Salem to Indianapolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Winston-Salem to Indianapolis.

Make a music playlist for your bus ride from Winston-Salem to Indianapolis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Winston-Salem by bus?

Bus from Indianapolis to Winston-Salem

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