Find coaches from Wilmington, DE to Chicago

Next departures

Next departures from Wilmington to Chicago on 15 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Delaware Rest Stop S
Downtown Greyhound StationCheapest
FlixBus + Greyhound Lines, Inc.
Delaware Rest Stop S
Chicago 95Th & Dan RyanFastest
Greyhound Lines, Inc. + FlixBus
Wilmington Bus Station
Chicago 95Th & Dan RyanNo tags
Greyhound Lines, Inc.
Wilmington Bus Station
Chicago 95Th & Dan RyanNo tags
Greyhound Lines, Inc.
Wilmington Bus Station
Chicago 95Th & Dan RyanNo tags

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Compare 2 ways to travel from Wilmington to Chicago

Bus
Average priceUS$69 - US$236Average duration1d 3h
26kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$111 - US$444Average duration22h 15m
95kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Wilmington to Chicago

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 3 hours 10 minutes and with fares starting at just US$69, it presents an excellent value for a comfortable ride.

26bus per day
1d 3hAverage duration
US$69Cheapest ticket
26kgCO₂ emissions

Bus Wilmington, DE to Chicago: Trip Overview

Average ticket priceUS$116
Average bus trip duration1d 3h
Number of daily buses26
Earliest bus departure02:50
Distance639 miles
Latest bus departure21:25

Wilmington to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Wilmington to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Wilmington to Chicago from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from Wilmington, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Wilmington, DE - Chicago

  1. What's the distance between Wilmington and Chicago by coach?

    The journey from Wilmington to Chicago by coach covers an approximate distance of 649 miles (1046 km).

  2. How can I travel from Wilmington to Chicago avoiding air travel?

    To travel from Wilmington to Chicago without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/09
US$90
13/09
US$81
Today
US$103
15/09
US$81
16/09
US$81
17/09
US$75
18/09
US$79
19/09
US$91
busbud logoThe cheapest trip from Wilmington, DE to Chicago was searched and found on 17 Sept 2025 with a price of US$75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Chicago as early as possible.

You can expect to pay from US$75 to US$183 for a bus ticket from Wilmington, DE to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$75, which is on 2025-09-17.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Wilmington to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Wilmington to Chicago, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Wilmington to Chicago.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Wilmington to Chicago.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Wilmington, DE to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Wilmington, DE by bus?

Bus from Chicago to Wilmington, DE

You can also go to Chicago by train

Train from Wilmington, DE to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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