Next departures to Chicago
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: 23 June atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: 24 June atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: Amtrak
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: 23 June atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: 24 June atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: BusDuration:
- Departure time: 23 June atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: 24 June atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: BusDuration:
- Departure time: 23 June atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: 24 June atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: BusDuration:
- Departure time: 23 June atDeparture city: Santa FeDeparture location: Santa Fe StationArrival time: 24 June atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: BusDuration:
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Bus Santa Fe to Chicago: Trip Overview
Compare bus companies
Based on 5225 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at US$161
Santa Fe to Chicago Bus
With Busbud, comparing and booking tickets for a bus from Santa Fe to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Santa Fe to Chicago from the most reliable bus companies operating this trip.
Discover how much the bus trip from Santa Fe to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Santa Fe and Chicago?
Frequently asked questions on the trip Santa Fe, US - Chicago
What's the distance between Santa Fe and Chicago by coach?
The journey from Santa Fe to Chicago by coach covers an approximate distance of 1070 miles (1725 km).
How can I travel from Santa Fe to Chicago avoiding air travel?
To travel from Santa Fe to Chicago without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Fe to Chicago was searched and found on 23 Jun 2025 with a price of US$384To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe to Chicago as early as possible.
You can expect to pay from US$384 to US$1,241 for a bus ticket from Santa Fe to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$384, which is on 2025-06-23.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Santa Fe to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santa Fe to Chicago, get comfy and count the stars.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Santa Fe to Chicago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Fe to Chicago.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top travelled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.