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- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: FastestDeparture time: 8 June atDeparture city: Panama CityDeparture location: Panama City Beach StationArrival time: 9 June atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: 8 June atDeparture city: Panama CityDeparture location: Panama City Beach StationArrival time: 9 June atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: 8 June atDeparture city: Panama CityDeparture location: Panama City Beach StationArrival time: 10 June atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
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Bus Panama City to Chicago: Trip Overview
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Based on 87021 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at US$215.00
Panama City to Chicago Bus
Busbud helps you find a bus from Panama City to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Panama City to Chicago.
Discover how much the bus trip from Panama City to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Panama City and Chicago?
Frequently asked questions on the trip Panama City, US - Chicago
How much is the coach fare from Panama City to Chicago?
The price for a coach ticket from Panama City to Chicago starts at US$204, though the average is US$249. The actual price may differ based on factors like the time you plan to travel, the day of the week, and the coach service provider you select. Keep in mind that booking tickets on the day of travel might result in higher prices.
How long is the coach ride from Panama City to Chicago?
The average duration for a trip from Panama City to Chicago by coach is around 1d 19h. The quickest coach journey typically takes 1d 2h. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.
At what time is the first coach from Panama City to Chicago?
The first departure to Chicago is at 12:50. Keep in mind that departure times might change on weekends and holidays.
How far is Chicago from Panama City by coach?
The distance between Panama City and Chicago by coach is approximately 815 miles (1314 km).
What is the best way to go from Panama City to Chicago without flying?
You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.
Is there am overnight coach from Panama City to Chicago?
Yes, you can find buses leaving until 13:55 and arriving the next day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City to Chicago was searched and found on 8 Jun 2025 with a price of US$247To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City to Chicago as early as possible.
You can expect to pay from US$247 to US$307 for a bus ticket from Panama City to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$247, which is on 2025-06-08.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and Chicago!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Panama City to Chicago.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Panama City to Chicago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to Chicago.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Top travelled bus routes
Why choose Busbud?
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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Panama City
Buses Leaving from Panama City
- Bus from Panama City to Long Beach
- Coach Panama City - Miami
- Bus Panama City - San Jose
- Panama City - Atlanta
- Bus from Panama City to Orlando
- Coach Panama City - Tallahassee
- Bus Panama City - Vienna
- Panama City - Fort Lauderdale
- Bus from Panama City to Dayton
- Coach Panama City - Huntsville
- Bus Panama City - Kansas City
- Panama City - Boca Raton
- Bus from Panama City to Columbus
- Coach Panama City - Lafayette
- Bus Panama City - Kansas City
Buses Going to Panama City
- Bus from Miami to Panama City
- Coach Atlanta - Panama City
- Bus Tallahassee - Panama City
- Long Beach - Panama City
- Bus from Tampa to Panama City
- Coach Chicago - Panama City
- Bus San Jose - Panama City
- Orlando - Panama City
- Bus from Boca Raton to Panama City
- Coach Fort Lauderdale - Panama City
- Bus New York - Panama City
- Los Angeles - Panama City
- Bus from Cincinnati to Panama City
- Coach Indianapolis - Panama City
- Bus St. Petersburg - Panama City