How much is the bus ticket from Detroit to St. Louis?

The cheapest coach tickets from Detroit to St. Louis start from £52. The average price for this route is around £77. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from Detroit to St. Louis?

The average bus journey time from Detroit to St. Louis is 15h 50m, covering a distance of 454 miles. The fastest bus can take you there in 12h 25m and is operated by FlixBus .

Which bus companies service the Detroit to St. Louis route?

Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Detroit to St. Louis?

The earliest bus departs from Detroit to St. Louis at 06:40. And the latest bus departs at 23:25.

What are the CO₂ emissions for the bus trip from Detroit to St. Louis?

A bus journey from Detroit to St. Louis produces an estimated 18 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Which is the best bus company from Detroit to St. Louis?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87463 reviews.

Which company has the best Wi-Fi from Detroit to St. Louis?

Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company offers the most punctual service from Detroit to St. Louis?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Detroit to St. Louis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Detroit to St. Louis from £48 | Refundable Tickets

Next bus departures

Next departures from Detroit to St. Louis on 11 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	20:15	Detroit Bus Station	12h 40m	07:55	Gateway Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	16:20	Detroit Bus Station	15h 5m	06:25	Gateway Station	No tags
	Bus	23:25	Detroit Bus Station	16h 55m	15:20	Gateway Station	No tags

Next departures from Detroit to St. Louis on 12 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	23:25	Detroit Bus Station	16h 55m	15:20	Gateway Station	Cheapest
	Bus	20:15	Detroit Bus Station	12h 40m	07:55	Gateway Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	08:20	Detroit Bus Station	15h 50m	23:10	Gateway Station	No tags

Next departures from Detroit to St. Louis on 13 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	08:20	Detroit Bus Station	16h 5m	23:25	Gateway Station	Cheapest
Bus	20:15	Detroit Bus Station	12h 40m	07:55	Gateway Station	Fastest
Bus	23:25	Detroit Bus Station	16h 55m	15:20	Gateway Station	No tags

Next departures from Detroit to St. Louis on 14 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	23:25	Detroit Bus Station	16h 55m	15:20	Gateway Station	Cheapest
	Bus	20:15	Detroit Bus Station	12h 40m	07:55	Gateway Station	Fastest
	Bus	06:40	Detroit Bus Station	17h 45m	23:25	Gateway Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	16:20	Detroit Bus Station	15h 5m	06:25	Gateway Station	No tags

Next departures from Detroit to St. Louis on 15 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	16:20	Detroit Bus Station	15h 5m	06:25	Gateway Station	Cheapest
	Bus	20:15	Detroit Bus Station	12h 40m	07:55	Gateway Station	Fastest
	Bus	07:15	Detroit Bus Station	17h 10m	23:25	Gateway Station	No tags
	Bus	23:15	Detroit Bus Station	17h 5m	15:20	Gateway Station	No tags

Next departures from Detroit to St. Louis on 18 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	20:15	Detroit Bus Station	12h 40m	07:55	Gateway Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	08:20	Detroit Bus Station	15h 50m	23:10	Gateway Station	No tags
	Bus	23:15	Detroit Bus Station	17h 5m	15:20	Gateway Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	16:20	Detroit Bus Station	15h 5m	06:25	Gateway Station	No tags

Last refresh of the prices: Yesterday at 10:01 EST.

Compare 2 ways to travel from Detroit to St. Louis

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach St. Louis. The journey takes about 13 hours 48 minutes and with fares starting at just £58, it presents an excellent value for a comfortable ride.

2train per day

13h 48mAverage duration

455 milesDistance

67kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£52 - £131	Average duration15h 50m	CO₂ emissions 18kg CO₂e
Train	Average price£58 - £353	Average duration13h 48m	CO₂ emissions 67kg CO₂e

Where are the popular stops in Detroit and St. Louis?

Stops in Detroit

A
Detroit Bus Station
1001 Howard St, Detroit, MI 48226, USA
Visit page Map

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page Map

Compare bus companies

Greyhound

3.5/587,493 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

FlixBus

3.5/512,002 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling by bus from Detroit, MI to St. Louis

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Detroit to St. Louis?
The cheapest coach tickets from Detroit to St. Louis start from £52. The average price for this route is around £77. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Detroit to St. Louis?
The average bus journey time from Detroit to St. Louis is 15h 50m, covering a distance of 454 miles. The fastest bus can take you there in 12h 25m and is operated by FlixBus.
Which bus companies service the Detroit to St. Louis route?
Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Detroit to St. Louis?
The earliest bus departs from Detroit to St. Louis at 06:40. And the latest bus departs at 23:25.
What are the CO₂ emissions for the bus trip from Detroit to St. Louis?
A bus journey from Detroit to St. Louis produces an estimated 18 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Detroit to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which company has the best Wi-Fi from Detroit to St. Louis?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Detroit to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Detroit to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/01

£90

10/01

£81

Today

£82

12/01

£62

13/01

£58

14/01

£56

15/01

£60

16/01

£66

The cheapest trip from Detroit, MI to St. Louis was searched and found on 14 Jan 2026 with a price of £56

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to St. Louis as early as possible.

You can expect to pay from £56 to £90 for a bus ticket from Detroit, MI to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £56, which is on 2026-01-14.