Find coaches from Charleston, SC, US to Port Saint Lucie

Bus Charleston, SC, US to Port Saint Lucie: Trip Overview

Average ticket priceUS$128
Average bus trip duration12h
Number of daily buses1
Earliest bus departure15:15
Distance388 miles

Charleston to Port Saint Lucie Bus

With Busbud, comparing and booking tickets for a bus from Charleston to Port Saint Lucie is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Charleston to Port Saint Lucie will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Charleston to Port Saint Lucie, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Charleston, SC, US - Port Saint Lucie

  1. How far is Port Saint Lucie from Charleston by coach?

    The distance between Charleston and Port Saint Lucie by coach is approximately 380 miles (613 km).

  2. Is there a way to reach Port Saint Lucie from Charleston without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
27/08
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28/08
US$121
Today
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30/08
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31/08
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01/09
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busbud logoThe cheapest trip from Charleston, SC, US to Port Saint Lucie was searched and found on 28 Aug 2025 with a price of US$121

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Port Saint Lucie as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Charleston to Port Saint Lucie.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Charleston to Port Saint Lucie, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Charleston to Port Saint Lucie that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Charleston to Port Saint Lucie, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Charleston, SC, US by bus?

Bus from Port Saint Lucie to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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