Bus Tickets from Mexico City to Santa Ana, US

Find affordable bus tickets from Mexico City to Santa Ana, US with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen trips

One passenger / one way

  • Departure time: August 7 at
    Departure city: Mexico City
    Departure location: Mexico City Buenavista (San Pedro Santa Clara)
    Arrival time: August 10 at
    Destination city: Santa Ana
    Destination location: UC Irvine (Crawford Hall)
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 7 at
    Departure city: Mexico City
    Departure location: Mexico City Buenavista (San Pedro Santa Clara)
    Arrival time: August 10 at
    Destination city: Santa Ana
    Destination location: Anaheim Regional Transportation Intermodal Center
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 7 at
    Departure city: Mexico City
    Departure location: Mexico City Buenavista (San Pedro Santa Clara)
    Arrival time: August 10 at
    Destination city: Santa Ana
    Destination location: Anaheim Regional Transportation Intermodal Center
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: August 7 at
    Departure city: Mexico City
    Departure location: Mexico City Buenavista (San Pedro Santa Clara)
    Arrival time: August 10 at
    Destination city: Santa Ana
    Destination location: Santa Ana Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 7 at
    Departure city: Mexico City
    Departure location: Mexico City Buenavista (Forum)
    Arrival time: August 10 at
    Destination city: Santa Ana
    Destination location: Anaheim Regional Transportation Intermodal Center
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Mexico City to Santa Ana, US: Trip Overview

Average Ticket PriceUS$279
Average Bus Trip Duration2d 15h
Number of daily buses10
Earliest bus departure4:00pm
Distance2432 km
Latest bus departure10:25pm

Mexico City to Santa Ana Bus

Busbud helps you find a bus from Mexico City to Santa Ana. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Mexico City to Santa Ana.

Whether it is cheap bus tickets or more luxurious buses going to Santa Ana from Mexico City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Mexico City - Santa Ana, US

  1. What is the travel distance from Mexico City to Santa Ana?

    It's about 2445 km (1516 miles) from Mexico City to Santa Ana.

  2. What are the departure and arrival locations for buses traveling from Mexico City to Santa Ana?

    Buses departing from Norte in Mexico City will take you to Santa Ana Greyhound Bus Station in Santa Ana.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mexico City and Santa Ana!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Mexico City to Santa Ana.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mexico City to Santa Ana.

Tune out to the fine sounds of your best music playlist on your bus trip from Mexico City to Santa Ana while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Mexico City by bus?

Bus from Santa Ana, US to Mexico City

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Mexico City

Buses Leaving from Mexico City

Buses Going to Mexico City

Popular Buses Connecting Santa Ana

Buses Leaving from Santa Ana

Buses Going to Santa Ana