Bus Tickets from Lyon to Santander

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TodaySep 2
TomorrowSep 3
from US$65
ThuSep 4
FriSep 5
SatSep 6
SunSep 7
MonSep 8
from US$65
TueSep 9

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 3 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: September 4 at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 3 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: September 4 at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: September 4 at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: September 4 at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: September 4 at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:

Accepted payments

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Compare 2 ways to go from Lyon to Santander

Bus
Average PriceUS$98 - US$184Average Duration20h 5m
18kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average PriceUS$74 - US$74Average Duration11h
31kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from Lyon to Santander

Among the sustainable travel choices, the bus stands out as a good way to reach Santander. The journey takes about 20 hours 5 minutes, and with fares starting at just US$98, it presents an excellent value for a comfortable ride.

2bus per day
20h 5mAverage Duration
US$98Cheapest ticket
18kgCO₂ emissions

Bus Lyon to Santander: Trip Overview

Average Ticket PriceUS$143
Average Bus Trip Duration20h 5m
Number of daily buses2
Earliest bus departure5:10am
Distance729 km
Latest bus departure11:59pm

Lyon to Santander Bus

Busbud helps you find a bus from Lyon to Santander. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Lyon to Santander from the most reliable bus companies operating this trip.

Discover how much the bus trip from Lyon to Santander will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Lyon - Santander

  1. How much does a bus ticket from Lyon to Santander cost?

    The bus ticket price from Lyon to Santander starts at US$98. The best way to find cheap bus tickets from Lyon to Santander is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Lyon to Santander?

    The average travel time between Lyon and Santander is around 20h 5m, although the fastest bus will take about 12h 45m.This is the time it takes to travel the 732 km that separates the two cities.

  3. How many daily bus connections are there between Lyon and Santander?

    The number of buses from Lyon to Santander can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Lyon to Santander by comparing and selecting the bus that fits you travel style and budget on Busbud.

  4. Which bus companies travel from Lyon to Santander?

    When taking the bus from Lyon to Santander, you can travel comfortably and safely with FlixBus, ALSA, BlaBlaCar Bus.

  5. What are the departure and arrival stations when taking the bus from Lyon to Santander?

    Buses travelling between Lyon and Santander leave from Perrache or Lyon Airport and arrive at Calle Navas de Tolosa, 2, Santander Airport, Av. de los Castros 43A.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-31
US$60
09-01
US$54
Today
US$60
09-03
US$61
09-04
US$60
09-05
US$60
09-06
US$59
09-07
US$59
busbud logoThe cheapest trip from Lyon to Santander was searched and found on Sep 1, 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Santander, as early as possible.

You can expect to pay from US$54 to US$176 for a bus ticket from Lyon to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at US$59 which is on 2025-09-07.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Lyon and Santander!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Santander, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lyon to Santander will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Lyon to Santander.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Lyon by bus?

Bus from Santander to Lyon

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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