Find coaches from Lyon to Santander

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Today2 Sept
Tomorrow3 Sept
from US$65
Thu4 Sept
Fri5 Sept
Sat6 Sept
Sun7 Sept
Mon8 Sept
from US$65
Tue9 Sept

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 3 September at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: 4 September at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 3 September at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: 4 September at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:
  • Departure time: 3 September at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: 4 September at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:
  • Departure time: 3 September at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: 4 September at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:
  • Departure time: 3 September at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: 4 September at
    Destination city: Santander
    Destination location: Calle Navas de Tolosa, 2
    Operated by: ALSA INTERNACIONALALSA INTERNACIONAL
    Vehicle: BusDuration:

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Compare 2 ways to travel from Lyon to Santander

Bus
Average priceUS$98 - US$184Average duration20h 5m
18kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average priceUS$74 - US$74Average duration11h
31kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from Lyon to Santander

Among the sustainable travel choices, the bus stands out as a good way to reach Santander. The journey takes about 20 hours 5 minutes and with fares starting at just US$98, it presents an excellent value for a comfortable ride.

2bus per day
20h 5mAverage duration
US$98Cheapest ticket
18kgCO₂ emissions

Bus Lyon to Santander: Trip Overview

Average ticket priceUS$143
Average bus trip duration20h 5m
Number of daily buses2
Earliest bus departure05:10
Distance452 miles
Latest bus departure23:59

Lyon to Santander Bus

Busbud helps you find a bus from Lyon to Santander. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Lyon to Santander from the most reliable bus companies operating this trip.

Discover how much the bus trip from Lyon to Santander will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Lyon - Santander

  1. What's the distance between Lyon and Santander by coach?

    The distance between Lyon and Santander by coach is approximately 454 miles (732 km).

  2. What is the best way to go from Lyon to Santander without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/08
US$60
01/09
US$54
Today
US$60
03/09
US$61
04/09
US$60
05/09
US$60
06/09
US$59
07/09
US$59
busbud logoThe cheapest trip from Lyon to Santander was searched and found on 1 Sept 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Santander as early as possible.

You can expect to pay from US$54 to US$176 for a bus ticket from Lyon to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at US$59, which is on 2025-09-07.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Lyon and Santander!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Santander, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Lyon to Santander will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Lyon to Santander.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Lyon by bus?

Bus from Santander to Lyon

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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