Bus Tickets from Greenville, SC to Fort Myers

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Previously seen trips

One passenger / one way

  • Departure time: January 3 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: January 4 at
    Destination city: Fort Myers
    Destination location: Ft Myers Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: January 6 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: January 7 at
    Destination city: Fort Myers
    Destination location: Fort Myers-Cape Coral
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: January 11 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: January 12 at
    Destination city: Fort Myers
    Destination location: Fort Myers-Cape Coral
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: January 15 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: January 16 at
    Destination city: Fort Myers
    Destination location: Fort Myers-Cape Coral
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: January 19 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: January 20 at
    Destination city: Fort Myers
    Destination location: Fort Myers-Cape Coral
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:

Accepted payments

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Compare 2 ways to go from Greenville to Fort Myers

Average PriceUS$75 - US$198Average Duration22h
23kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$280 - US$526Average Duration1d 14h
83kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Fort Myers

Among the sustainable travel choices, the bus stands out as a good way to reach Fort Myers. The journey takes about 22 hours, and with fares starting at just US$75, it presents an excellent value for a comfortable ride.

4bus per day
22hAverage Duration
US$75Cheapest ticket
23kgCO₂ emissions

Bus Greenville, SC to Fort Myers: Trip Overview

Average Ticket PriceUS$107
Average Bus Trip Duration22h
Number of daily buses4
Earliest bus departure1:25pm
Distance912 km
Latest bus departure10:00pm

Greenville to Fort Myers Bus

Busbud helps you find a bus from Greenville to Fort Myers. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Greenville to Fort Myers will be provided by the most trusted bus companies.

Discover how much the bus trip from Greenville to Fort Myers will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - Fort Myers

  1. How much does a bus ticket from Greenville to Fort Myers cost?

    The bus ticket price from Greenville to Fort Myers starts at US$75. The best way to find cheap bus tickets from Greenville to Fort Myers is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Greenville to Fort Myers?

    The average travel time between Greenville and Fort Myers is around 22h, although the fastest bus will take about 19h.This is the time it takes to travel the 918 km that separates the two cities.

  3. How many daily bus connections are there between Greenville and Fort Myers?

    The number of buses from Greenville to Fort Myers can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Greenville to Fort Myers by comparing and selecting the bus that fits you travel style and budget on Busbud.

  4. Which bus companies travel from Greenville to Fort Myers?

    When taking the bus from Greenville to Fort Myers, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Greenville to Fort Myers?

    Buses travelling between Greenville and Fort Myers leave from Guadalajara Supermarket Bus Stop or Greenville Bus Station and arrive at Daniels Pkwy & I-75, Colonial Blvd & I-75, Rosa Parks.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-05
No data
09-06
No data
Today
US$102
09-08
US$85
09-09
No data
09-10
No data
09-11
No data
09-12
US$93
busbud logoThe cheapest trip from Greenville, SC to Fort Myers was searched and found on Sep 8, 2025 with a price of US$85

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Fort Myers, as early as possible.

You can expect to pay from US$85 to US$102 for a bus ticket from Greenville, SC to Fort Myers based on the last 2 days. You can expect to find the cheapest price for the trip at US$85 which is on 2025-09-08.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Fort Myers!

Much more than a mere vehicle taking you from Greenville to Fort Myers, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Fort Myers will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Fort Myers.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Greenville, SC to Fort Myers?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Fort Myers to Greenville, SC

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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