Bus Tickets from Fort Myers to Greenville (SC)

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Bus Fort Myers to Greenville: Trip Overview

Average Ticket PriceUS$128
Average Bus Trip Duration17h 5m
Number of daily buses2
Earliest bus departure2:25pm
Distance916 km
Latest bus departure6:35pm

Fort Myers to Greenville Bus

With Busbud, comparing and booking tickets for a bus from Fort Myers to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Fort Myers to Greenville.

From cheap bus tickets to more luxurious buses travelling from Fort Myers to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Fort Myers - Greenville (SC)

  1. How far is Fort Myers from Greenville?

    It's about 918 km (570 miles) from Fort Myers to Greenville.

  2. What are the departure and arrival locations for buses traveling from Fort Myers to Greenville?

    Buses departing from Daniels Pkwy & I-75 in Fort Myers will take you to Guadalajara Supermarket Bus Stop in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-16
No data
06-17
No data
Today
No data
06-19
US$229
06-20
US$335
06-21
US$324
06-22
US$293
06-23
No data
busbud logoThe cheapest trip from Fort Myers to Greenville was searched and found on Jun 19, 2025 with a price of US$229

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Fort Myers to Greenville, as early as possible.

You can expect to pay from US$229 to US$1,500 for a bus ticket from Fort Myers to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$229 which is on 2025-06-19.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Fort Myers to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Fort Myers to Greenville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Fort Myers to Greenville that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Fort Myers to Greenville.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Fort Myers by bus?

Bus from Fort Myers to Greenville

You can also go to Greenville by train

Train from Fort Myers to Greenville

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