Bus Tickets from Detroit (MI) to Greenville (SC)

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TodayJun 1
TomorrowJun 2
from US$148
TueJun 3
WedJun 4
ThuJun 5
FriJun 6
SatJun 7
SunJun 8

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 2 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 3 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 2 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 3 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 2 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 3 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Today at 12:08 PM EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Detroit to Greenville

Average PriceUS$77 - US$333Average Duration1d
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$459 - US$459Average Duration1d 19h
76kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Detroit to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 50 minutes, and with fares starting at just US$77, it presents an excellent value for a comfortable ride.

2bus per day
1d Average Duration
US$77Cheapest ticket
21kgCO₂ emissions

Bus Detroit to Greenville: Trip Overview

Average Ticket PriceUS$105
Average Bus Trip Duration1d
Number of daily buses2
Earliest bus departure6:40am
Distance836 km
Latest bus departure11:25pm

Detroit to Greenville Bus

With Busbud, comparing and booking tickets for a bus from Detroit to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Detroit to Greenville will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Detroit to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Detroit (MI) - Greenville (SC)

  1. How long does it take to get to Greenville from Detroit by bus?

    The bus ride from Detroit to Greenville takes 1d, on average. For the shortest travel time, select the fastest bus available, which will take you to Greenville in about 18h 20m.

  2. What is the distance between Detroit and Greenville?

    Detroit and Greenville are 835 km (518 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Detroit to Greenville?

    Buses departing from Detroit Bus Station in Detroit will take you to Guadalajara Supermarket Bus Stop in Greenville.

  4. What is the cheapest way to get from Detroit to Greenville?

    The least expensive option to go from Detroit to Greenville would be going by bus. The ticket price for this bus starts at US$77, making this your best choice for this trip.

  5. How much is the bus from Detroit to Greenville?

    The bus from Detroit to Greenville will cost you US$105, on average.

  6. Is it possible to travel by overnight bus from Detroit to Greenville?

    Yes! If you're heading from Detroit to Greenville, you'll find buses departing until 11:25pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-30
No data
05-31
No data
Today
No data
06-02
US$141
06-03
No data
06-04
US$93
06-05
US$92
06-06
US$90
busbud logoThe cheapest trip from Detroit to Greenville was searched and found on Jun 6, 2025 with a price of US$90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit to Greenville, as early as possible.

You can expect to pay from US$90 to US$164 for a bus ticket from Detroit to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$90 which is on 2025-06-06.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Detroit to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Detroit to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Detroit to Greenville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Detroit to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Detroit to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Detroit by bus?

Bus from Detroit to Greenville

You can also go to Greenville by train

Train from Detroit to Greenville

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