Bus Tickets from San Francisco, US to San Ysidro, CA

Find affordable bus tickets from San Francisco, US to San Ysidro, CA with flexible options. Book your trip now

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TodayAug 30
from $67
TomorrowAug 31
from $84
MonSep 1
from $95
TueSep 2
from $78
WedSep 3
from $67
ThuSep 4
from $78
FriSep 5
SatSep 6

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 31 at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: August 31 at
    Destination city: San Ysidro
    Destination location: San Ysidro Bus terminal
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 31 at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: September 1 at
    Destination city: San Ysidro
    Destination location: San Ysidro Bus terminal
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: September 1 at
    Destination city: San Ysidro
    Destination location: San Ysidro Bus terminal
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: San Francisco
    Departure location: San Francisco Bus Station
    Arrival time: September 1 at
    Destination city: San Ysidro
    Destination location: San Ysidro Bus terminal
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: San Francisco
    Departure location: San Francisco Bus Station
    Arrival time: August 31 at
    Destination city: San Ysidro
    Destination location: San Ysidro Bus terminal
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Bus San Francisco, US to San Ysidro, CA: Trip Overview

Average ticket price$84
Average bus trip duration13h 10m
Number of daily buses5
Earliest bus departure6:30am
Distance471 miles (759 km)
Latest bus departure11:25pm

San Francisco to San Ysidro Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Francisco to San Ysidro.

Bus service from San Francisco to San Ysidro will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to San Ysidro from San Francisco, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip San Francisco, US - San Ysidro, CA

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/28
$98
08/29
$90
Today
$60
08/31
$77
09/01
$90
09/02
$70
09/03
$60
09/04
$70
busbud logoThe cheapest trip from San Francisco, US to San Ysidro, CA was searched and found on Aug 30, 2025 with a price of $60

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to San Ysidro, CA, as early as possible.

You can expect to pay from $60 to $138 for a bus ticket from San Francisco, US to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $60 which is on 2025-09-03.

Usually FlixBus, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Francisco to San Ysidro but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from San Francisco to San Ysidro, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Francisco to San Ysidro.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Francisco to San Ysidro.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to San Francisco, US by bus?

Bus from San Ysidro, CA to San Francisco, US

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