Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Knoxville Bus Station | Tuscaloosa Greyhound Bus Station | CheapestFastest |
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Bus Knoxville, TN to Tuscaloosa: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Knoxville to Tuscaloosa Bus
Busbud helps you find a bus from Knoxville to Tuscaloosa. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Tuscaloosa.
Whether it is cheap bus tickets or more luxurious buses going to Tuscaloosa from Knoxville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Knoxville and Tuscaloosa?
Frequently asked questions for your trip Knoxville, TN - Tuscaloosa
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Tuscaloosa was searched and found on Sep 3, 2025 with a price of $42To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Tuscaloosa, as early as possible.
You can expect to pay from $42 to $66 for a bus ticket from Knoxville, TN to Tuscaloosa based on the last 2 days. You can expect to find the cheapest price for the trip at $42 which is on 2025-09-03.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Knoxville and Tuscaloosa!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Knoxville to Tuscaloosa.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Tuscaloosa.
Tune out to the fine sounds of your best music playlist on your bus trip from Knoxville to Tuscaloosa while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top traveled bus routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Orlando
- Bus Knoxville - Chicago
- Knoxville - Miami
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - Memphis
- Bus from Knoxville to New York City
- Bus Knoxville - Washington
- Knoxville - Asheville
- Bus from Knoxville to Jackson
- Bus Knoxville - Cincinnati
- Knoxville - Roanoke
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Richmond - Knoxville
- Bus from Atlanta to Knoxville
- Bus Asheville - Knoxville
- New York City - Knoxville
- Bus from Greenville to Knoxville
- Bus Louisville - Knoxville
- Lexington - Knoxville
- Bus from Cookeville to Knoxville
- Bus Dallas - Knoxville
- Dayton - Knoxville
Popular Buses Connecting Tuscaloosa
Buses Leaving from Tuscaloosa
- Bus from Tuscaloosa to Atlanta
- Bus Tuscaloosa - Birmingham
- Tuscaloosa - Madison
- Bus from Tuscaloosa to Mobile
- Bus Tuscaloosa - Monroe
- Tuscaloosa - Nashville
- Bus from Tuscaloosa to LaGrange
- Bus Tuscaloosa - Huntsville
- Tuscaloosa - Hattiesburg
- Bus from Tuscaloosa to New Orleans
- Bus Tuscaloosa - Montgomery
- Tuscaloosa - Chicago
- Bus from Tuscaloosa to Memphis
- Bus Tuscaloosa - Charlotte
- Tuscaloosa - Tallahassee
Buses Going to Tuscaloosa
- Bus from Burlington to Tuscaloosa
- Bus Atlanta - Tuscaloosa
- Birmingham - Tuscaloosa
- Bus from Riverside to Tuscaloosa
- Bus Auburn - Tuscaloosa
- Buffalo - Tuscaloosa
- Bus from New Orleans to Tuscaloosa
- Bus Nashville - Tuscaloosa
- Orlando - Tuscaloosa
- Bus from Montgomery to Tuscaloosa
- Bus Mobile - Tuscaloosa
- Gainesville - Tuscaloosa
- Bus from New York City to Tuscaloosa
- Bus Houston - Tuscaloosa
- Tallahassee - Tuscaloosa
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Miami - Tampa
- Bus from Seattle to Leavenworth
- Bus Austin - Dallas
- Dallas - Austin
- Bus from Houston to San Antonio
- Bus Austin - Houston
- Orlando - Atlanta
- Bus from New York City to Los Angeles
- Bus Dallas - San Antonio
- Houston - Austin