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Bus Knoxville, TN to San Antonio, US: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Knoxville San Antonio recent customer reviews
My bus was late showing up in Dallas my 6:30 bus either left or was late not sure but they just about didn't let me on the 8:30 bus to San Antonio
Chris R.
Knoxville to San Antonio Bus
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Where are the popular stops in Knoxville and San Antonio?
Frequently asked questions for your trip Knoxville, TN - San Antonio, US
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Knoxville to San Antonio.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Knoxville to San Antonio, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Knoxville to San Antonio will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to San Antonio.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top traveled bus routes
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Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Orlando
- Bus Knoxville - Chicago
- Knoxville - Lubbock
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - Memphis
- Bus from Knoxville to New York City
- Bus Knoxville - Washington
- Knoxville - Asheville
- Bus from Knoxville to Miami
- Bus Knoxville - Jackson
- Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Asheville - Knoxville
- New York City - Knoxville
- Bus from Greenville to Knoxville
- Bus Louisville - Knoxville
- Lexington - Knoxville
- Bus from Cookeville to Knoxville
- Bus Dallas - Knoxville
- Dayton - Knoxville
Popular Buses Connecting San Antonio
Buses Leaving from San Antonio
- Bus from San Antonio to Austin
- Bus San Antonio - Live Oak
- San Antonio - Las Vegas
- Bus from San Antonio to Houston
- Bus San Antonio - Dallas
- San Antonio - Denver
- Bus from San Antonio to Eagle Pass
- Bus San Antonio - Laredo
- San Antonio - El Paso
- Bus from San Antonio to Fort Worth
- Bus San Antonio - McAllen
- San Antonio - Corpus Christi
- Bus from San Antonio to Chicago
- Bus San Antonio - Katy
- San Antonio - Atlanta
Buses Going to San Antonio
- Bus from San Fernando to San Antonio
- Bus Burlington - San Antonio
- Austin - San Antonio
- Bus from Corpus Christi to San Antonio
- Bus Denver - San Antonio
- New Orleans - San Antonio
- Bus from Eagle Pass to San Antonio
- Bus Laredo - San Antonio
- El Paso - San Antonio
- Bus from McAllen to San Antonio
- Bus Katy - San Antonio
- Fort Worth - San Antonio
- Bus from Killeen to San Antonio
- Bus College Station - San Antonio
- San Angelo - San Antonio
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Miami - Tampa
- Bus from Seattle to Leavenworth
- Bus Austin - Dallas
- Dallas - Austin
- Bus from Houston to San Antonio
- Bus Austin - Houston
- Orlando - Atlanta
- Bus from New York City to Los Angeles
- Bus Dallas - San Antonio
- Houston - Austin
Popular airport transfers
- Travel in United States
- Bus to Knoxville, TN
- Bus to San Antonio, US
- Knoxville, TN to San Antonio, US Buses