Bus Tickets from Denver to San Diego (CA), US

Find affordable bus tickets from Denver to San Diego (CA), US with flexible options. Book your trip now

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TodayMay 27
TomorrowMay 28
ThuMay 29
FriMay 30
SatMay 31
from $112
SunJun 1
MonJun 2
TueJun 3

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: May 31 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: June 1 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: June 1 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: June 1 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Denver
    Departure location: Denver Bus Station
    Arrival time: June 2 at
    Destination city: San Diego
    Destination location: Cross Border Xpress CBX (USA)
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: June 2 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Denver to San Diego.

Average Price$67 - $328Average Duration1d 11h
34kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average Price$188 - $188Average Duration1d 21h
122kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Denver to San Diego

Among the sustainable travel choices, the bus stands out as the good way to reach San Diego. The journey takes about 1 day, 11 hours 15 minutes and with fares starting at just $67, it presents an excellent value for a comfortable ride.

16bus per day
1d 11hAverage Duration
$67Cheapest ticket
34kgCO₂ emissions

Bus Denver to San Diego: Trip Overview

Average ticket price$163
Average bus trip duration1d 11h
Number of daily buses16
Earliest bus departure9:45am
Distance831 miles (1340 km)
Latest bus departure7:50pm

Denver to San Diego Bus

Busbud helps you find a bus from Denver to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Denver to San Diego.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from Denver, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Denver - San Diego (CA), US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/25
$201
05/26
$117
Today
$136
05/28
$195
05/29
$145
05/30
$174
05/31
$105
06/01
$95
busbud logoThe cheapest trip from Denver to San Diego was searched and found on Jun 1, 2025 with a price of $95

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to San Diego, as early as possible.

You can expect to pay from $95 to $237 for a bus ticket from Denver to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at $95 which is on 2025-06-01.

Usually LLIO will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Denver and San Diego!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Denver to San Diego.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Denver to San Diego.

Tune out to the fine sounds of your best music playlist on your bus trip from Denver to San Diego while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Denver to San Diego?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Denver by bus?

Bus from Denver to San Diego

You can also go to San Diego by train

Train from Denver to San Diego

Why choose Busbud?

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