Bus and Train from Pisa to Rome: Tickets & Timetables

Next available departures

Next departures from Pisa to Rome on 12 April
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
park Aurelia
Rome Tiburtina Bus StationCheapest
Trenitalia FRECCIABIANCA
Piazza della Stazione, 10
TerminiFastest
MarinoBus
Fermata dell'autobus Pisa
Rome Tiburtina Bus StationNo tags
Busitalia
Fermata dell'autobus Pisa
Rome Tiburtina Bus StationNo tags
Trenitalia FRECCIABIANCA
Piazza della Stazione, 10
TerminiNo tags

Last refresh of the prices: Today at 07:49 CEST.

Compare 2 ways to travel from Pisa to Rome

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 3 hours 44 minutes and with fares starting at just £18, it presents an excellent value for a comfortable ride.

9train per day
3h 44mAverage duration
164 milesDistance
6kgCO₂ emissions
Average price£12 - £123Average duration5h 50m
7kg CO₂e
Average price£18 - £154Average duration3h 44m
6kg CO₂e

Frequently asked questions about travelling from Pisa to Rome by bus or train

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much does a ticket from Pisa to Rome cost?

    The cheapest tickets from Pisa to Rome start from £12. The average price for this route is around £23. Busbud recommends that you book your tickets in advance for a better chance of getting the lowest possible price.

  2. How long is the journey from Pisa to Rome?

    The average trip duration from Pisa to Rome is 4h 47m, covering a distance of 165 miles. The quickest vehicle can get you there in 2h 9m and is operated by Trenitalia.

  3. Which companies operate the Pisa to Rome route?

    Several major companies operate on this route with 10 trips available per day, including services from FlixBus, BusItalia, MarinoBus, Itabus, Trenitalia.

  4. What are the earliest and latest departure times from Pisa to Rome?

    The earliest service departs from Pisa for Rome at 00:25. And the latest service departs at 23:30.

  5. What are the CO₂ emissions for the journey from Pisa to Rome?

    A journey from Pisa to Rome produces an estimated 6.641562500000001 kg of CO₂, making it a highly eco-friendly way to travel and a mode of transport recommended by Busbud.

  6. Which is the best company from Pisa to Rome?

    According to Busbud customers, the highest-rated company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 918 reviews.

  7. Which company has the best Wi-Fi from Pisa to Rome?

    According to reviews on Busbud, the company BusItalia has the best Wi-Fi rating with a score of 3.7.

  8. Which company offers the most punctual service from Pisa to Rome?

    According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.

  9. Which company has the cleanest vehicles from Pisa to Rome?

    According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.

Find the cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/04
£24
10/04
£24
Today
£15
12/04
£13
13/04
£11
14/04
£11
15/04
£15
16/04
£11
busbud logoThe cheapest trip from Pisa to Rome was searched and found on 13 Apr 2026 with a price of £11

To save money and ensure you get the best seat, it's a good idea to buy your bus and train tickets from Pisa to Rome, as early as possible.

You can expect to pay between £11 and £132 for a bus or train ticket from Pisa to Rome based on the past 2 days. You can expect to find the lowest price for the trip at £11 on 2026-04-13.

Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Pisa to Rome?

busbud logoThe Bus is the cheapest travel choice for this destination

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