Bus from Pisa to Rome: Tickets & Schedules

Next bus departures

Next departures for Pisa to Rome on December 18
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus Bus
Parcheggio Via Pietransantina
Rome Tiburtina Bus StationCheapest
Flixbus Bus
Parcheggio Via Pietransantina
Rome Tiburtina Bus StationFastest
MarinoBusBus
Fermata dell'autobus Pisa
Rome Tiburtina Bus StationNo tags
Flixbus Bus
park Aurelia
Rome Tiburtina Bus StationNo tags
Flixbus Bus
Parcheggio Via Pietransantina
Rome Tiburtina Bus StationNo tags

Last refresh of the prices: Yesterday at 10:58 PM CET.

Compare 3 ways to go from Pisa to Rome

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Rome. The journey takes about 3 hours 50 minutes and with fares starting at just $18, it presents an excellent value for a comfortable ride.

13carpool per day
3h 50mAverage Duration
165 milesDistance
11kgCO₂ emissions
Average Price$14 - $154Average Duration6h
7kg CO₂e
Average Price$21 - $205Average Duration3h 51m
6kg CO₂e
Carpool
Average Price$18 - $49Average Duration3h 50m
11kg CO₂e

Frequently asked questions about traveling from Pisa to Rome by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Pisa to Rome?

    The cheapest bus tickets from Pisa to Rome start from $14. The average price for this route is around $28. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Pisa to Rome?

    The average bus trip duration from Pisa to Rome is 6h, covering a distance of 165 miles (265 km). The quickest bus can get you there in 4h 14m and is operated by BusItalia.

  3. Which bus companies service the Pisa to Rome route?

    Several major bus companies operate on this route with 11 buses available per day, including services from FlixBus, BusItalia, MarinoBus, Itabus, GoOpti.

  4. What is the earliest and latest departure time for the bus from Pisa to Rome?

    The earliest bus departs from Pisa to Rome at 12:25am. And the latest bus departs at 11:45pm.

  5. What are the CO₂ emissions for the bus trip from Pisa to Rome?

    A bus trip from Pisa to Rome generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Pisa to Rome?

    According to Busbud customers, the highest-rated bus company on this route is GoOpti, with an average rating of 4.6 out of 5 stars based on 140 reviews.

  7. Which bus company has the best Wi-Fi from Pisa to Rome?

    Based on reviews on Busbud, the bus company GoOpti has the best Wi-Fi rating with a score of 4.0.

  8. Which bus company has the most timely service from Pisa to Rome?

    According to Busbud traveller reviews, the most timely bus company on this route is GoOpti, with a punctuality rating of 4.8 out of 5 stars.

  9. Which bus company has the cleanest buses from Pisa to Rome?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is GoOpti, with a cleanliness rating of 4.8 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/15
$21
12/16
$25
Today
$26
12/18
$21
12/19
$20
12/20
$20
12/21
$22
12/22
$17
busbud logoThe cheapest trip from Pisa to Rome was searched and found on Dec 22, 2025 with a price of $17

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Rome, as early as possible.

You can expect to pay from $17 to $150 for a bus ticket from Pisa to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $17 which is on 2025-12-22.

What's the cheapest way to go from Pisa to Rome?

busbud logoThe bus is the cheapest travel choice for this destination

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