Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Parcheggio Via Pietransantina | Milan (San Donato M3) | Cheapest | |||||
 | Piazza della Stazione, 10 | Milano Centrale | Fastest | |||||
| Piazza della Stazione, 10 | Milano Centrale | No tags | |||||
| Parcheggio Via Pietransantina | Milan (Malpensa Airport Terminal 1) | No tags | |||||
| Piazza della Stazione, 10 | Milano Centrale | No tags |
Last refresh of the prices: Yesterday at 9:44 PM CEST.
Compare 2 ways to go from Pisa to Milano
Among the sustainable travel choices, the Bus stands out as a good way to reach Milano. The journey takes about 6 hours and with fares starting at just $18, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Milano?
Stops in Pisa
- APiazza della Stazione, 10, 56125 Pisa PI, Italy
- CVia Pietrasantina, 56123 Pisa PI
- D
Stazione Ferroviaria Pisa Centrale - Fermata dell'autobus
Via Giuseppe Sainati 16, 56121 Pisa PI, Italy - E
Tombolo
Via Aurelia, 325, 56121 Pisa PI, Italy - F
San Rossore
56122 Pisa PI, Italy
Stops in Milano
- APiazza Duca d'Aosta 1, 20124 Milano MI, Italy
- BVia Gamboloita 7, 20139 Milano MI, Italy
- C20017 Rho MI, Italy
- DPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- EVia Giulio Natta, 228, 20151 Milano, Italy
- FP.za Sigmund Freud 1, 20124 Milano MI, Italy
Compare companies
Frequently asked questions about traveling from Pisa to Milano by bus or train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is a ticket from Pisa to Milano?
The cheapest tickets from Pisa to Milano start from $18. The average price for this route is around $43. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the ride from Pisa to Milano?
The average trip duration from Pisa to Milano is 5h 32m, covering a distance of 133 miles (215 km). The quickest vehicle can get you there in 3h 44m and is operated by Trenitalia.
Which companies service the Pisa to Milano route?
Several major companies operate on this route with 8 trips available per day, including services from FlixBus, Itabus, Trenitalia.
What is the earliest and latest departure time from Pisa to Milano?
The earliest trip departs from Pisa to Milano at 4:45am. And the latest trip departs at 11:30pm.
What are the CO₂ emissions for the trip from Pisa to Milano?
A trip from Pisa to Milano generates an estimated 5.354712500000001 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best company from Pisa to Milano?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 3.9 out of 5 stars based on 58 reviews.
Which company has the best Wi-Fi from Pisa to Milano?
Based on reviews on Busbud, the company Itabus has the best Wi-Fi rating with a score of 3.0.
Which company has the most timely service from Pisa to Milano?
According to Busbud traveler reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.
Which company has the cleanest vehicles from Pisa to Milano?
According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Milano was searched and found on Apr 15, 2026 with a price of $16To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Pisa to Milano, as early as possible.
You can expect to pay from $16 to $89 for a bus or train ticket from Pisa to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $16 which is on 2026-04-15.
Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
