Find coaches from Santiago, CL to San Luis, AR

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Previously seen journeys

One passenger / one way

  • Departure time: 15 July at
    Departure city: Santiago
    Departure location: Santiago De Chile
    Arrival time: 15 July at
    Destination city: San Luis
    Destination location: Ediro San Luis
    Operated by: Tu EnvidiaTu Envidia
    Vehicle: BusDuration:
  • Departure time: 18 July at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: 18 July at
    Destination city: San Luis
    Destination location: Terminal de San Luis
    Operated by: Via Bariloche + Buses Ahumada Internacional
    Via Bariloche + Buses Ahumada Internacional
    Vehicle: BusDuration:
  • Departure time: 18 July at
    Departure city: Santiago
    Departure location: Terminal Los Héroes
    Arrival time: 18 July at
    Destination city: San Luis
    Destination location: Terminal de San Luis
    Operated by: Via Bariloche + Buses Ahumada Internacional
    Via Bariloche + Buses Ahumada Internacional
    Vehicle: BusDuration:
  • Departure time: 22 July at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: 22 July at
    Destination city: San Luis
    Destination location: Estación de Interconexión Regional de Ómnibus de San Luis
    Operated by: Andesmar + CATA Internacional
    Andesmar + CATA Internacional
    Vehicle: BusDuration:
  • Departure time: 22 July at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: 22 July at
    Destination city: San Luis
    Destination location: Estación de Interconexión Regional de Ómnibus de San Luis
    Operated by: Andesmar + Del Sur y Media Agua
    Andesmar + Del Sur y Media Agua
    Vehicle: BusDuration:

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Bus Santiago, CL to San Luis, AR: Trip Overview

Average ticket priceUS$83
Average bus trip duration9h
Number of daily buses2
Earliest bus departure07:30
Distance253 miles
Latest bus departure12:00

Santiago to San Luis Bus

With Busbud, comparing and booking tickets for a bus from Santiago to San Luis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Santiago to San Luis from the most reliable bus companies operating this trip.

Discover how much the bus trip from Santiago to San Luis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Santiago, CL - San Luis, AR

  1. What's the distance between Santiago and San Luis by coach?

    The journey from Santiago to San Luis by coach covers an approximate distance of 245 miles (394 km).

  2. How can I get from Santiago to San Luis without driving?

    You can reach San Luis from Santiago by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/09
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05/09
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Today
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08/09
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09/09
US$58
10/09
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11/09
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busbud logoThe cheapest trip from Santiago, CL to San Luis, AR was searched and found on 9 Sept 2025 with a price of US$58

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to San Luis, AR as early as possible.

You can expect to pay from US$58 to US$69 for a bus ticket from Santiago, CL to San Luis, AR based on the last 2 days. You can expect to find the cheapest price for the trip at US$58, which is on 2025-09-09.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Santiago to San Luis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santiago to San Luis, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Santiago to San Luis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Santiago to San Luis while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Santiago, CL by bus?

Bus from San Luis, AR to Santiago, CL

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