Find coaches from Santiago, BR to Florianópolis

Find affordable coach tickets from Santiago, BR to Florianópolis with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen journeys

One passenger / one way

  • Departure time: 16 September at
    Departure city: Santiago
    Departure location: Estação Rodoviária De Santiago
    Arrival time: 17 September at
    Destination city: Florianópolis
    Destination location: Rodoviária de Florianópolis
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: 17 September at
    Departure city: Santiago
    Departure location: Santiago Onibus
    Arrival time: 18 September at
    Destination city: Florianópolis
    Destination location: Rodoviária de Florianópolis
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: 22 September at
    Departure city: Santiago
    Departure location: Santiago Onibus
    Arrival time: 23 September at
    Destination city: Florianópolis
    Destination location: Rodoviária de Florianópolis
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: 8 October at
    Departure city: Santiago
    Departure location: Estação Rodoviária De Santiago
    Arrival time: 9 October at
    Destination city: Florianópolis
    Destination location: Rodoviária de Florianópolis
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: 17 November at
    Departure city: Santiago
    Departure location: Santiago Onibus
    Arrival time: 18 November at
    Destination city: Florianópolis
    Destination location: Rodoviária de Florianópolis
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Santiago, BR to Florianópolis: Trip Overview

Average ticket priceUS$67
Average bus trip duration15h 50m
Number of daily buses1
Earliest bus departure15:00
Distance398 miles

Santiago to Florianópolis Bus

With Busbud, comparing and booking tickets for a bus from Santiago to Florianópolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Santiago to Florianópolis will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Santiago to Florianópolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santiago, BR - Florianópolis

  1. What's the distance between Santiago and Florianópolis by coach?

    The journey from Santiago to Florianópolis by coach covers an approximate distance of 399 miles (643 km).

  2. How can I travel from Santiago to Florianópolis avoiding air travel?

    To travel from Santiago to Florianópolis without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/08
No data
30/08
No data
Today
US$57
01/09
No data
02/09
No data
03/09
No data
04/09
No data
05/09
No data
busbud logoThe cheapest trip from Santiago, BR to Florianópolis was searched and found on 31 Aug 2025 with a price of US$57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, BR to Florianópolis as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Santiago to Florianópolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Santiago to Florianópolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santiago to Florianópolis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Santiago to Florianópolis while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Santiago, BR by bus?

Bus from Florianópolis to Santiago, BR

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Santiago

Buses Leaving from Santiago

Buses Going to Santiago

Popular Buses Connecting Florianópolis

Buses Leaving from Florianópolis

Buses Going to Florianópolis