Cheap buses leaving tomorrow
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: 21 June atDeparture city: New CastleDeparture location: Route 422 Park & RideArrival time: 22 June atDestination city: St LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Accepted payments
Bus New Castle to St Louis: Trip Overview
Compare bus companies
Based on 87045 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at US$128
New Castle to St Louis Bus
With Busbud, comparing and booking tickets for a bus from New Castle to St Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from New Castle to St Louis will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from New Castle to St Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Frequently asked questions on the trip New Castle - St Louis
How far is St Louis from New Castle by coach?
The distance between New Castle and St Louis by coach is approximately 551 miles (888 km).
Is there a way to reach St Louis from New Castle without flying?
You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from New Castle to St Louis was searched and found on 21 Jun 2025 with a price of US$120To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Castle to St Louis as early as possible.
You can expect to pay from US$120 to US$120 for a bus ticket from New Castle to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$120, which is on 2025-06-21.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from New Castle to St Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from New Castle to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from New Castle to St Louis that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from New Castle to St Louis while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting New Castle
Buses Leaving from New Castle
- Bus from New Castle to New York
- Coach New Castle - Washington
- Bus New Castle - Pittsburgh
- New Castle - Philadelphia
- Bus from New Castle to Birmingham
- Coach New Castle - Manchester
- Bus New Castle - Columbus
- New Castle - Grand Rapids
- Bus from New Castle to Zelienople
- Coach New Castle - Miami
- Bus New Castle - St Louis
- New Castle - Richmond
- Bus from New Castle to Fort Walton Beach
- Coach New Castle - Gadsden
- Bus New Castle - Cincinnati
Buses Going to New Castle
- Bus from Pittsburgh to New Castle
- Coach Philadelphia - New Castle
- Bus Indianapolis - New Castle
- Chicago - New Castle
- Bus from Richmond to New Castle
- Coach Newark - New Castle
- Bus Springfield - New Castle
- Allentown - New Castle
- Bus from Phoenix to New Castle
- Coach St Louis - New Castle
- Bus Harrisburg - New Castle
- Columbus - New Castle
- Bus from Albany to New Castle
- Coach Boston - New Castle
- Bus Florence - New Castle