Cheap buses leaving Saturday
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: 21 June atDeparture city: HarrisburgDeparture location: Harrisburg Bus StationArrival time: 22 June atDestination city: St LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: 21 June atDeparture city: HarrisburgDeparture location: Harrisburg Bus StationArrival time: 21 June atDestination city: St LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: 21 June atDeparture city: HarrisburgDeparture location: HarrisburgArrival time: 22 June atDestination city: St LouisDestination location: Gateway StationOperated by: FlixBus
Vehicle: BusDuration: - Departure time: 21 June atDeparture city: HarrisburgDeparture location: Harrisburg Bus StationArrival time: 22 June atDestination city: St LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: 21 June atDeparture city: HarrisburgDeparture location: Harrisburg Bus StationArrival time: 22 June atDestination city: St LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
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Compare 2 ways to travel from Harrisburg to St Louis
Busbud recommends taking the bus from Harrisburg to St LouisAmong the sustainable travel choices, the bus stands out as a good way to reach St Louis. The journey takes about 22 hours 5 minutes and with fares starting at just US$117, it presents an excellent value for a comfortable ride.
Bus Harrisburg to St Louis: Trip Overview
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Harrisburg to St Louis Bus
With Busbud, comparing and booking tickets for a bus from Harrisburg to St Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Harrisburg to St Louis.
Discover how much the bus trip from Harrisburg to St Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Harrisburg and St Louis?
Frequently asked questions on the trip Harrisburg - St Louis
How far is St Louis from Harrisburg by coach?
The distance between Harrisburg and St Louis by coach is approximately 718 miles (1158 km).
Is there a way to reach St Louis from Harrisburg without flying?
You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Harrisburg to St Louis was searched and found on 21 Jun 2025 with a price of US$109To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to St Louis as early as possible.
You can expect to pay from US$109 to US$187 for a bus ticket from Harrisburg to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$109, which is on 2025-06-21.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Harrisburg to St Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Harrisburg to St Louis.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Harrisburg to St Louis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Make a music playlist for your bus ride from Harrisburg to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
What's the cheapest way to go from Harrisburg to St Louis?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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