Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus station | Camden (Walter Rand Transportation Center) | Cheapest | |||||
 | Florence, SC | Philadelphia, 199 Spring Garden St | Fastest | |||||
FlixBus + Greyhound Lines, Inc. | Bus station | 199 Spring Garden St. | No tags | |||||
| Bus station | Philadelphia, 199 Spring Garden St | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Bus station | Schuylkill & Walnut | No tags |
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Compare 2 ways to travel from Florence to Philadelphia
Busbud recommends taking the train from Florence to PhiladelphiaAmong the sustainable travel choices, the train stands out as a good way to reach Philadelphia. The journey takes about 10 hours 18 minutes and with fares starting at just US$97, it presents an excellent value for a comfortable ride.
Bus Florence, SC, US to Philadelphia, PA: Trip Overview
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Florence to Philadelphia Bus
Busbud helps you find a bus from Florence to Philadelphia. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Philadelphia.
From cheap bus tickets to more luxurious buses travelling from Florence to Philadelphia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Florence and Philadelphia?
Frequently asked questions on the trip Florence, SC, US - Philadelphia, PA
What's the distance between Florence and Philadelphia by coach?
The distance between Florence and Philadelphia by coach is approximately 467 miles (753 km).
What is the best way to go from Florence to Philadelphia without flying?
You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Philadelphia, PA was searched and found on 22 Sept 2025 with a price of US$58To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Philadelphia, PA as early as possible.
You can expect to pay from US$58 to US$112 for a bus ticket from Florence, SC, US to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at US$58, which is on 2025-09-22.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Florence and Philadelphia!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Philadelphia.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Philadelphia that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Philadelphia.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
What's the cheapest way to go from Florence, SC, US to Philadelphia, PA?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Florence
Buses Leaving from Florence
- Bus from Florence to Kansas City
- Coach Florence - Kansas City
- Bus Florence - Oklahoma City
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- Bus from Florence to Houston
- Coach Florence - Montgomery
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- Coach Florence - Gary
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Buses Going to Florence
- Bus from Syracuse to Florence
- Coach Manchester - Florence
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- Columbus - Florence
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- Coach Washington - Florence
- Bus Opelika - Florence
- Miami - Florence
- Bus from New York City to Florence
- Coach Panama City - Florence
- Bus Charleston - Florence
Popular Buses Connecting Philadelphia
Buses Leaving from Philadelphia
- Bus from Philadelphia to Richmond
- Coach Philadelphia - Washington
- Bus Philadelphia - Washington
- Philadelphia - Washington
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- Coach Philadelphia - Queens Village
- Bus Philadelphia - Baltimore
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- Coach Philadelphia - Miami
- Bus Philadelphia - Newark
- Philadelphia - Scranton
- Bus from Philadelphia to Chicago
- Coach Philadelphia - Boston
- Bus Philadelphia - Springfield
Buses Going to Philadelphia
- Bus from Marathon to Philadelphia
- Coach North East - Philadelphia
- Bus Pittsburgh - Philadelphia
- Boston - Philadelphia
- Bus from Washington to Philadelphia
- Coach Washington - Philadelphia
- Bus Newark - Philadelphia
- Savannah - Philadelphia
- Bus from Allentown to Philadelphia
- Coach Reading - Philadelphia
- Bus Scranton - Philadelphia
- Baltimore - Philadelphia
- Bus from Easton to Philadelphia
- Coach Albany - Philadelphia
- Bus Richmond - Philadelphia
Popular routes in this country
- Bus from Niagara Falls to New York City
- Coach Atlanta - Savannah
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- Washington - Baltimore
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- Coach Houston - Dallas
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- Bus New York City - Baltimore