Find coaches from Florence, SC, US to Jacksonville, FL

Find affordable coach tickets from Florence, SC, US to Jacksonville, FL with flexible options. Book your journey now

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Today24 Aug
from US$61
Tomorrow25 Aug
from US$51
Tue26 Aug
from US$55
Wed27 Aug
from US$51
Thu28 Aug
from US$51
Fri29 Aug
from US$56
Sat30 Aug
from US$51
Sun31 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 25 August at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: 25 August at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 25 August at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: 25 August at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Accepted payments

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Compare 2 ways to travel from Florence to Jacksonville

Bus
Average priceUS$51 - US$86Average duration5h 45m
12kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$64 - US$145Average duration12h 28m
42kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Florence to Jacksonville

Among the sustainable travel choices, the bus stands out as a good way to reach Jacksonville. The journey takes about 5 hours 45 minutes and with fares starting at just US$51, it presents an excellent value for a comfortable ride.

2bus per day
5h 45mAverage duration
US$51Cheapest ticket
12kgCO₂ emissions

Bus Florence, SC, US to Jacksonville, FL: Trip Overview

Average ticket priceUS$61
Average bus trip duration5h 45m
Number of daily buses2
Earliest bus departure05:45
Distance289 miles
Latest bus departure12:55

Florence to Jacksonville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Jacksonville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Jacksonville.

Whether it is cheap bus tickets or more luxurious buses going to Jacksonville from Florence, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Florence, SC, US - Jacksonville, FL

  1. How far is Jacksonville from Florence by coach?

    The distance between Florence and Jacksonville by coach is approximately 293 miles (472 km).

  2. Is there a way to reach Jacksonville from Florence without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
22/08
US$54
23/08
US$43
Today
US$45
25/08
US$43
26/08
US$47
27/08
US$43
28/08
US$43
29/08
US$48
busbud logoThe cheapest trip from Florence, SC, US to Jacksonville, FL was searched and found on 23 Aug 2025 with a price of US$43

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Jacksonville, FL as early as possible.

You can expect to pay from US$43 to US$65 for a bus ticket from Florence, SC, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at US$43, which is on 2025-08-25.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Jacksonville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Jacksonville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Jacksonville.

Make a music playlist for your bus ride from Florence to Jacksonville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Florence, SC, US to Jacksonville, FL?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence, SC, US by bus?

Bus from Jacksonville, FL to Florence, SC, US

You can also go to Jacksonville, FL by train

Train from Florence, SC, US to Jacksonville, FL

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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