Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Durham Station | Greyhound Amtrak Station | CheapestFastest | ||||
| Train | Durham Station | Greyhound Amtrak Station | No tags |
Last refresh of the prices: Last Monday at 12:07 AM EST.
Compare 2 ways to go from Durham to Indianapolis
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 23 hours 20 minutes, and with fares starting at just $172, it presents an excellent value for a comfortable ride.
Train companies
Based on 5671 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $204
Frequently asked questions about travelling from Durham, NC, US to Indianapolis by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Durham to Indianapolis?
The cheapest train tickets from Durham to Indianapolis start at $204. The average price for this train route is around $384. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Durham to Indianapolis?
The average train trip from Durham to Indianapolis takes 1d 11h and covers 762 km. The quickest train gets you there in 1d 10h and is operated by Amtrak.
Which train operators serve the Durham to Indianapolis route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Durham to Indianapolis?
The earliest train from Durham to Indianapolis departs at 6:04pm. The latest train departs at 7:06pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Indianapolis was searched and found on Dec 23, 2025 with a price of $394To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Durham, NC, US to Indianapolis, as early as possible.
You can expect to pay from $394 to $1,456 for a train ticket from Durham, NC, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $394 which is on 2025-12-25.
