Bus Tickets from Pittsburgh to Greenville (SC)

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Compare 2 ways to go from Pittsburgh to Greenville

Bus
Average PriceUS$115 - US$302Average Duration18h 45m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$269 - US$404Average Duration21h 54m
60kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Pittsburgh to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 18 hours 45 minutes, and with fares starting at just US$115, it presents an excellent value for a comfortable ride.

3bus per day
18h 45mAverage Duration
US$115Cheapest ticket
16kgCO₂ emissions

Bus Pittsburgh to Greenville: Trip Overview

Average Ticket PriceUS$167
Average Bus Trip Duration18h 45m
Number of daily buses3
Earliest bus departure1:35am
Distance657 km
Latest bus departure11:10pm

Pittsburgh to Greenville Bus

With Busbud, comparing and booking tickets for a bus from Pittsburgh to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Pittsburgh to Greenville.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Pittsburgh, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Pittsburgh - Greenville (SC)

  1. How long is the trip from Pittsburgh to Greenville by bus?

    The bus ride from Pittsburgh to Greenville takes 18h 45m, on average. For the shortest travel time, select the fastest bus available, which will take you to Greenville in about 18h.

  2. What is the travel distance from Pittsburgh to Greenville?

    Pittsburgh and Greenville are 657 km (408 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Pittsburgh to Greenville?

    Buses departing from Intermodal Station in Pittsburgh will take you to Guadalajara Supermarket Bus Stop in Greenville.

  4. What is the cheapest way to get from Pittsburgh to Greenville?

    The least expensive option to go from Pittsburgh to Greenville would be going by bus. The ticket price for this bus starts at US$115, making this your best choice for this trip.

  5. How much does the bus ticket cost from Pittsburgh to Greenville?

    The bus from Pittsburgh to Greenville will cost you US$167, on average.

  6. Is there an overnight bus from Pittsburgh to Greenville?

    Yes! If you're heading from Pittsburgh to Greenville, you'll find buses departing until 11:10pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
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06-07
US$235
Today
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busbud logoThe cheapest trip from Pittsburgh to Greenville was searched and found on Jun 7, 2025 with a price of US$235

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Greenville, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Pittsburgh to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Pittsburgh to Greenville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Pittsburgh to Greenville.

Tune out to the fine sounds of your best music playlist on your bus trip from Pittsburgh to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Pittsburgh to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Pittsburgh by bus?

Bus from Pittsburgh to Greenville

You can also go to Greenville by train

Train from Pittsburgh to Greenville

Why choose Busbud?

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