Bus Tickets from Gainesville (FL) to Panama City, US

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Bus Gainesville to Panama City: Trip Overview

Average Ticket PriceUS$75
Average Bus Trip Duration6h 10m
Number of daily buses1
Earliest bus departure8:30am
Distance333 km

Gainesville to Panama City Bus

With Busbud, comparing and booking tickets for a bus from Gainesville to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Gainesville to Panama City from the most reliable bus companies operating this trip.

Discover how much the bus trip from Gainesville to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Gainesville (FL) - Panama City, US

  1. How long is the trip from Gainesville to Panama City by bus?

    The bus ride from Gainesville to Panama City takes 6h 10m, on average. For the shortest travel time, select the fastest bus available, which will take you to Panama City in about 6h 10m.

  2. What is the travel distance from Gainesville to Panama City?

    Gainesville and Panama City are 328 km (204 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Gainesville to Panama City?

    Buses departing from Rosa Parks Station in Gainesville will take you to Panama City Greyhound Bus Station in Panama City.

  4. What is the cheapest way to get from Gainesville to Panama City?

    The least expensive way to go from Gainesville to Panama City would be going by bus. With a starting ticket price of US$75, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from Gainesville to Panama City?

    The bus from Gainesville to Panama City will cost you US$75, on average.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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US$47
busbud logoThe cheapest trip from Gainesville to Panama City was searched and found on Jun 3, 2025 with a price of US$47

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville to Panama City, as early as possible.

You can expect to pay from US$47 to US$47 for a bus ticket from Gainesville to Panama City based on the last 2 days. You can expect to find the cheapest price for the trip at US$47 which is on 2025-06-03.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Gainesville to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Gainesville to Panama City, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Gainesville to Panama City will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Gainesville to Panama City.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Gainesville by bus?

Bus from Gainesville to Panama City

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