Bus Tickets from San Diego, CA, US to Mesa

Next departures

Next departures for San Diego to Mesa on August 27
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
UCSD Health La Jolla Station
Mesa Bus StopCheapest
FlixBus + Greyhound Lines, Inc.
UCSD Health La Jolla Station
Mesa Bus StopFastest
FlixBus + Greyhound Lines, Inc.
San Diego (Old Town-FlixBus)
Mesa Bus StopNo tags
Greyhound Lines, Inc.
Greyhound Bus Stop
Mesa Bus StopNo tags
FlixBus + Greyhound Lines, Inc.
San Diego (Old Town-FlixBus)
Mesa Bus StopNo tags

Accepted payments

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Bus San Diego, CA, US to Mesa: Trip Overview

Average ticket price$63
Average bus trip duration12h 45m
Number of daily buses10
Earliest bus departure7:15am
Distance313 miles (504 km)
Latest bus departure7:35pm

San Diego to Mesa Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Mesa is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Mesa.

Whether it is cheap bus tickets or more luxurious buses going to Mesa from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip San Diego, CA, US - Mesa

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/19
No data
08/20
No data
Today
No data
08/22
No data
08/23
$51
08/24
$50
08/25
$59
08/26
$62
busbud logoThe cheapest trip from San Diego, CA, US to Mesa was searched and found on Aug 24, 2025 with a price of $50

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Mesa, as early as possible.

You can expect to pay from $50 to $62 for a bus ticket from San Diego, CA, US to Mesa based on the last 2 days. You can expect to find the cheapest price for the trip at $50 which is on 2025-08-24.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Diego to Mesa.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Diego to Mesa.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to Mesa.

Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to Mesa while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to San Diego, CA, US by bus?

Bus from Mesa to San Diego, CA, US

Why choose Busbud?

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