Bus Tickets from San Antonio, US to San Diego, CA, US

Next departures

Next departures for San Antonio to San Diego on September 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
San Antonio Bus Station
UCSD Health La Jolla StationCheapest
Greyhound Lines, Inc.
San Antonio Bus Station
Greyhound Bus StopFastest
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus
San Antonio Bus Station
San Diego (Old Town-FlixBus)No tags
Greyhound Lines, Inc.
San Antonio Bus Station
Greyhound Bus StopNo tags
Valley Transit + Greyhound Lines, Inc.
San Antonio Bus Station
Greyhound Bus StopNo tags

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Compare 2 ways to go from San Antonio to San Diego.

Bus
Average Price$117 - $448Average Duration1d 18h
45kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$159 - $353Average Duration1d 9h
165kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from San Antonio to San Diego

Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 1 day, 9 hours 5 minutes and with fares starting at just $159, it presents an excellent value for a comfortable ride.

2train per day
1d 9hAverage Duration
$159Cheapest ticket
165kgCO₂ emissions

Bus San Antonio, US to San Diego, CA, US: Trip Overview

Average ticket price$184
Average bus trip duration1d 18h
Number of daily buses16
Earliest bus departure1:30am
Distance1127 miles (1817 km)
Latest bus departure9:00pm

San Antonio to San Diego Bus

With Busbud, comparing and booking tickets for a bus from San Antonio to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from San Antonio to San Diego will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from San Antonio to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Antonio, US - San Diego, CA, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/28
$189
08/29
No data
Today
No data
08/31
No data
09/01
$180
09/02
No data
09/03
No data
09/04
$171
busbud logoThe cheapest trip from San Antonio, US to San Diego, CA, US was searched and found on Sep 4, 2025 with a price of $171

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to San Diego, CA, US, as early as possible.

You can expect to pay from $171 to $189 for a bus ticket from San Antonio, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $171 which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Antonio to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from San Antonio to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Antonio to San Diego that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from San Antonio to San Diego while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from San Antonio, US to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Antonio, US by bus?

Bus from San Diego, CA, US to San Antonio, US

You can also go to San Diego, CA, US by train

Train from San Antonio, US to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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