Bus Tickets from Rochester, NY, US to Harrisburg

Find affordable bus tickets from Rochester, NY, US to Harrisburg with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 24
from $83
TomorrowJun 25
from $71
ThuJun 26
from $74
FriJun 27
from $131
SatJun 28
from $104
SunJun 29
from $133
MonJun 30
from $87
TueJul 1

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 25 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 25 at
    Destination city: Harrisburg
    Destination location: Harrisburg Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 25 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 26 at
    Destination city: Harrisburg
    Destination location: Harrisburg Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 25 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 25 at
    Destination city: Harrisburg
    Destination location: Harrisburg Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 25 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 25 at
    Destination city: Harrisburg
    Destination location: Harrisburg
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: June 25 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: June 26 at
    Destination city: Harrisburg
    Destination location: Harrisburg Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Rochester to Harrisburg.

Bus
Average Price$71 - $200Average Duration14h 50m
8kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$118 - $331Average Duration12h 15m
30kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Rochester to Harrisburg

Among the sustainable travel choices, the train stands out as the good way to reach Harrisburg. The journey takes about 12 hours 15 minutes and with fares starting at just $118, it presents an excellent value for a comfortable ride.

3train per day
12h 15mAverage Duration
$118Cheapest ticket
30kgCO₂ emissions

Bus Rochester to Harrisburg: Trip Overview

Average ticket price$94
Average bus trip duration14h 50m
Number of daily buses7.7857142857142865
Earliest bus departure12:35am
Distance204 miles (328 km)
Latest bus departure11:50pm

Rochester to Harrisburg Bus

Busbud helps you find a bus from Rochester to Harrisburg. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Rochester to Harrisburg from the most reliable bus companies operating this trip.

Discover how much the bus trip from Rochester to Harrisburg will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Rochester, NY, US - Harrisburg

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/22
$154
06/23
$82
Today
$75
06/25
$63
06/26
$66
06/27
$131
06/28
$97
06/29
$139
busbud logoThe cheapest trip from Rochester to Harrisburg was searched and found on Jun 25, 2025 with a price of $63

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester to Harrisburg, as early as possible.

You can expect to pay from $63 to $157 for a bus ticket from Rochester to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $63 which is on 2025-06-25.

Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Rochester and Harrisburg!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rochester to Harrisburg, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rochester to Harrisburg will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Rochester to Harrisburg while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Rochester to Harrisburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Rochester by bus?

Bus from Rochester to Harrisburg

You can also go to Harrisburg by train

Train from Rochester to Harrisburg

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Rochester

Buses Leaving from Rochester

Buses Going to Rochester

Popular Buses Connecting Harrisburg

Buses Leaving from Harrisburg

Buses Going to Harrisburg