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- This trip is recommended because it is: Cheapest + FastestDeparture time: August 3 atDeparture city: Panama CityDeparture location: Panama City Beach StationArrival time: August 6 atDestination city: San JoseDestination location: Diridon StationOperated by: Greyhound Lines, Inc.
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Bus Panama City, US to San Jose, US: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Panama City to San Jose Bus
Busbud helps you find a bus from Panama City to San Jose. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Panama City to San Jose from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Panama City to San Jose, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Panama City and San Jose?
Frequently asked questions for your trip Panama City, US - San Jose, US
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Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to San Jose, US was searched and found on Aug 3, 2025 with a price of $391To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to San Jose, US, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and San Jose!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to San Jose, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Panama City to San Jose that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to San Jose.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Panama City
Buses Leaving from Panama City
- Bus from Panama City to Long Beach
- Bus Panama City - Miami
- Panama City - San Jose
- Bus from Panama City to Atlanta
- Bus Panama City - Orlando
- Panama City - Tallahassee
- Bus from Panama City to Tampa
- Bus Panama City - Fort Lauderdale
- Panama City - Jacksonville
- Bus from Panama City to Biloxi
- Bus Panama City - New York City
- Panama City - New Orleans
- Bus from Panama City to Gainesville
- Bus Panama City - Dothan
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Buses Going to Panama City
- Bus from Miami to Panama City
- Bus Tallahassee - Panama City
- Atlanta - Panama City
- Bus from Tampa to Panama City
- Bus Chicago - Panama City
- San Jose - Panama City
- Bus from Orlando to Panama City
- Bus Jacksonville - Panama City
- Fort Lauderdale - Panama City
- Bus from Houston to Panama City
- Bus Dothan - Panama City
- New Orleans - Panama City
- Bus from New York City to Panama City
- Bus Fort Myers - Panama City
- Lake City - Panama City